PDF(Pubmed)
Abstract：
Background and Objectives: Superb microvascular imaging is an advanced Doppler algorithm that seems to be useful in detecting low-velocity blood flow without using a contrast agent. Increasing evidence suggests that SMI is a more sensitive tool than conventional Doppler techniques for evaluating rheumatic diseases, especially inflammatory arthritis. We aimed to assess the use of SMI in evaluating joints and extraarticular structures. Materials and Methods: Two reviewers independently reviewed the literature to provide a global overview of the possibilities of SMI in rheumatology. Original English-language articles published between February 2014 and November 2022 were identified through database (PubMed, Medline, Ebsco, the Cochrane Library, and ScienceDirect) searching, and analysed to summarise existing evidence according to PRISMA methodology. Inclusion criteria covered original research articles reporting applications of SMI on rheumatic diseases and musculoskeletal disorders secondary to rheumatic conditions. Qualitative data synthesis was performed. Results: A total of 18 articles were included. No systematic reviews fulfilled our inclusion criteria. Most studies focused on characterising the synovial vascularity of rheumatoid arthritis. There have been several attempts to demonstrate SMI\'s value for evaluating extra-articular soft tissues (fat pads or salivary glands) and large-diameter vessels. The quantitative importance of SMI vascular indices could become a useful non-invasive diagnostic marker. Studies on therapeutic applications are still scarce, and the majority of studies have gaps in reporting the methodology (ultrasound performance technique and settings) of the research. Conclusions: SMI has proved to be useful in characterising low-flow vascularity, and growing evidence indicates that SMI is a non-invasive and lower-cost tool for prognostic assessment, especially in inflammatory arthritis. Preliminary findings also suggest potential interest in evaluating the effect of treatment.
摘要：
背景和目的：超微血管成像是一种先进的多普勒算法，似乎在不使用造影剂的情况下可用于检测低速血流。越来越多的证据表明，SMI是一种比传统的多普勒技术更敏感的工具来评估风湿性疾病，尤其是炎性关节炎.我们旨在评估SMI在评估关节和关节外结构中的应用。材料和方法：两名审阅者独立回顾了文献，以提供SMI在风湿病中的可能性的全球概述。通过数据库（PubMed，Medline,Ebsco,Cochrane图书馆,和ScienceDirect)搜索，并根据PRISMA方法进行分析以总结现有证据。纳入标准涵盖了报告SMI在风湿性疾病和风湿性疾病继发的肌肉骨骼疾病中的应用的原始研究文章。进行定性数据合成。结果:共纳入18篇文献。没有系统评价符合我们的纳入标准。大多数研究集中在表征类风湿性关节炎的滑膜血管。已经有几次尝试证明SMI对评估关节外软组织（脂肪垫或唾液腺）和大直径血管的价值。SMI血管指数的定量重要性可能成为有用的非侵入性诊断标记。关于治疗应用的研究仍然很少，大多数研究在报告研究的方法（超声性能技术和设置）方面存在差距。结论：SMI已被证明可用于表征低流量血管，越来越多的证据表明，SMI是一种非侵入性和低成本的预后评估工具，尤其是炎性关节炎.初步发现还表明对评估治疗效果的潜在兴趣。
