PDF(Pubmed)
Abstract：
Miscarriage is one of the most frequent adverse events that occurs during pregnancy. This retrospective study aimed to verify if the environmental and socioeconomic conditions related to geographical areas where women live, and the socio-demographic and clinical factors play a role in the risk of spontaneous abortion (SA). The analyses were conducted by hospital discharge records (HDRs) from public and private hospitals in Apulia from 1 January 2021 to 31 December 2021. Women with an age over 40 years old had a major risk of SA compared with women under 18 years (OR 2.30, IC95%1.16-4.54). A reduction in the risk of SA was found for women with an endocrinological or metabolic disease (OR 0.28, 95% CI 0.19-0.41), while genetic disease greatly increases the risk (OR 9.63, IC95% 1.98-46.86). The greatest risk of spontaneous abortion was found in the province of Taranto compared to the province of Foggia (OR 2.01, 95% CI 1.52-2.64). The provinces with a higher risk of SA in the multiple comparisons were Taranto, Brindisi, and BAT. Municipalities with socioeconomic disadvantages classified as very low, low, and medium had a higher risk of SA compared to the municipalities with a high disadvantage. In conclusion, our study indicates the possible association between SA rate and environmental conditions. Additionally, the socioeconomic, clinical, and demographic factors were related to the risk of SAs.
摘要：
流产是怀孕期间最常见的不良事件之一。这项回顾性研究旨在验证环境和社会经济条件是否与女性居住的地理区域有关，社会人口统计学和临床因素在自然流产（SA）的风险中起作用。分析是根据2021年1月1日至2021年12月31日在普利亚的公立和私立医院的出院记录（HDRs）进行的。与18岁以下的女性相比，年龄在40岁以上的女性具有SA的主要风险（OR2.30，IC95%1.16-4.54）。发现患有内分泌或代谢性疾病的女性患SA的风险降低（OR0.28，95％CI0.19-0.41），而遗传性疾病的风险大大增加（OR9.63，IC95%1.98-46.86）。与福贾省相比，塔兰托省自然流产的风险最大（OR2.01，95％CI1.52-2.64）。多重比较中SA风险较高的省份是塔兰托，布林迪西,还有BAT.社会经济劣势被归类为非常低的城市，低,与劣势较高的市政当局相比，中等有更高的SA风险。总之,我们的研究表明SA率与环境条件之间可能存在关联.此外,社会经济,临床,人口统计学因素与SAs风险相关。
