PDF(Pubmed)
Abstract：
Decreased arterial perfusion is a typical condition of patients with peripheral artery disease (PAD), with the microvascular picture particularly present among women. This observational study aimed to detect foot perfusion changes by infrared thermography (IRT) after a home-based exercise program in both sexes. A total of 76 PAD patients with claudication (72 ± 4 years; 52 males) were enrolled in a structured in-home exercise program composed of two daily 8 min interval walking sessions (1:1 walk:rest ratio) with progressively increasing speed. Outcome measures collected at baseline (T0) and at each hospital visit after 5 weeks, 12 weeks and 20 weeks included foot temperature measured by IRT (anterior tibial, posterior tibial, dorsalis pedis and arcuate artery regions), ankle brachial index and the 6 min walking test. After 20 weeks, foot temperature in both limbs showed a significant increasing trend, with a mean variation of 1.3 °C for the more impaired limb and 0.9 °C for the contralateral limb (t = 8.88, p < 0.001 and t = 5.36; p < 0.001, respectively), with significant changes occurring after 5 weeks of training. The sex-oriented analysis did not highlight any significant difference, with an improvement of mean foot temperature of 1.5 ± 0.6 °C in females versus 1.2 ± 0.5 °C in males (p = 0.42). Ankle brachial index and performance also significantly improved over time (p < 0.001) without gender differences. In patients with PAD, a structured low-intensity exercise program significantly improved foot temperature and exercise capacity without any sex-related difference.
摘要：
动脉灌注减少是外周动脉疾病(PAD)患者的典型病症,微血管图片尤其存在于女性中。这项观察性研究旨在通过红外热像仪（IRT）检测两性家庭锻炼计划后的足部灌注变化。共有76例PADlau行患者（72±4岁；52例男性）参加了结构化的家庭锻炼计划，该计划由两次每天8分钟的间隔步行（步行：休息比1：1）组成，速度逐渐增加。在基线（T0）和5周后每次医院就诊时收集的结果测量值，12周和20周包括通过IRT测量的足部温度（胫骨前，胫骨后端,足背和弓形动脉区域)，踝臂指数和6分钟步行试验。20周后,双肢足温呈明显上升趋势,受损肢体的平均变异为1.3°C，对侧肢体的平均变异为0.9°C（t=8.88，p<0.001和t=5.36；p<0.001），训练5周后发生显著变化。性别导向分析没有突出任何显著差异，女性平均足温改善为1.5±0.6°C，男性为1.2±0.5°C（p=0.42）。踝臂指数和表现也随着时间的推移而显著改善(p<0.001),没有性别差异。在PAD患者中，结构化的低强度运动计划显着改善了足部温度和运动能力，而没有任何与性别相关的差异。
