关键词: EEG correlates autism spectrum disorder cognitive functions white matter signal abnormalities

来  源:   DOI:10.3390/diagnostics13182878   PDF(Pubmed)

Abstract:
This research aimed to examine the EEG correlates of different stimuli processing instances in a child with ASD and white matter signal abnormalities and to investigate their relationship to the results of behavioral tests. The prospective case study reports two and a half years of follow-up data from a child aged 38 to 66 months. Cognitive, speech-language, sensory, and EEG correlates of auditory-verbal and auditory-visual-verbal information processing were recorded during five test periods, and their mutual interrelation was analyzed. EEG findings revealed no functional theta frequency range redistribution in the frontal regions favoring the left hemisphere during speech processing. The results pointed to a positive linear trend in the relative theta frequency range and a negative linear trend in the relative alpha frequency range when listening to and watching the cartoon. There was a statistically significant correlation between EEG signals and behavioral test results. Based on the obtained results, it may be concluded that EEG signals and their association with the results of behavioral tests should be evaluated with certain restraints considering the characteristics of the stimuli during EEG recording.
摘要:
这项研究旨在检查患有ASD和白质信号异常的儿童的不同刺激处理实例的EEG相关性,并研究它们与行为测试结果的关系。前瞻性案例研究报告了一名38至66个月儿童的两年半随访数据。Cognitive,语音语言,感官,在五个测试期间记录了听觉-言语和听觉-视觉-言语信息处理的EEG相关性,并分析了它们之间的相互关系。EEG的发现表明,在语音处理过程中,额叶区域没有功能theta频率范围的重新分布,这有利于左半球。结果表明,在收听和观看动画片时,相对theta频率范围呈正线性趋势,相对alpha频率范围呈负线性趋势。EEG信号与行为测试结果之间存在统计学上的显着相关性。根据获得的结果,可以得出结论,考虑到EEG记录过程中刺激的特征,应在一定的约束下评估EEG信号及其与行为测试结果的关联。
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