PDF(Pubmed)
Abstract：
Many patients with cancer make use of complementary medicine alongside conventional medicine, but clinicians in oncology often lack the knowledge to adequately advise patients on the evidence base for complementary therapies. This study aims to provide an overview of recently published systematic reviews that assess the effects of complementary therapies on patient-reported health outcomes in patients with cancer. Systematic reviews, including a meta-analysis of at least two randomized controlled trials, were identified from the PubMed, Embase, Cochrane Library, CINAHL and PsycINFO databases. The methodological quality was assessed with AMSTAR 2. One hundred systematic reviews were included. The results suggest that several complementary therapies can improve health outcomes reported by patients with cancer, such as acupuncture to relieve pain, music interventions to reduce anxiety and yoga to improve cancer-related fatigue. The side effects related to complementary therapy use are generally mild. The results remain inconclusive for some intervention-outcome combinations. Many of the included systematic reviews insufficiently assessed the causes and impact of bias in their interpretation of the results. This overview of systematic reviews can support clinicians in counselling their patients on this topic and provide directions for future research and clinical practice guidelines in the field of complementary medicine.
摘要：
许多癌症患者与常规药物一起使用补充药物，但肿瘤学的临床医生往往缺乏足够的知识来为患者提供补充治疗的证据基础.这项研究旨在提供最近发表的系统评价的概述，以评估补充疗法对癌症患者报告的健康结果的影响。系统审查，包括至少两项随机对照试验的荟萃分析，是从PubMed上确认的，Embase,科克伦图书馆,CINAHL和PsycINFO数据库。使用AMSTAR2评估方法学质量。包括了一百次系统审查。结果表明，几种补充疗法可以改善癌症患者报告的健康结果，比如针灸来缓解疼痛，音乐干预，以减少焦虑和瑜伽，以改善癌症相关的疲劳。与使用补充疗法相关的副作用通常是轻微的。对于某些干预-结果组合，结果仍不确定。许多纳入的系统评价在解释结果时没有充分评估偏见的原因和影响。这种系统评价的概述可以支持临床医生就该主题为患者提供咨询，并为补充医学领域的未来研究和临床实践指南提供指导。
