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Abstract：
We investigated the occurrence of organochlorine pollutants (OCs) in the muscle of brown trout and evaluated their potential modulation of parasite infection. The toxicological risk for consumer health was assessed, too. Trout were collected from the Sila National Park (Calabria region, South of Italy). The highest concentrations emerged for the sum of the 6 non-dioxin-like (ndl) indicator polychlorinated biphenyls (Σ6ndl-PCBs), followed by the 1,1,1-trichloro-2,2-di(4-chlorophenyl)-ethane (DDT), dioxin-like PCBs, hexachlorobenzene (HCB), and dieldrin. Measured on lipid weight (LW), the mean value of Σ6ndl-PCBs amounted to 201.9 ng g-1, that of ΣDDTs (the sum of DDT-related compounds) to 100.2 ng g-1, with the major contribution of the DDT-metabolite p,p\'-DDE which was detected in all sample units (97.6 ng g-1 on average). Among dioxin-like congeners, PCB 118 showed the highest mean concentration (21.96 ng g-1 LW) and was detected in all sample units. Regression analysis of intestinal parasites on OC concentration was performed, controlling for two potential confounding factors, namely sex and sexual stage. The results evidenced the existence of interactions between the dual stressors in the host-parasite system in the wild. A negative and statistically significant correlation was estimated, suggesting that OCs may decrease parasite infection degree. Regarding the toxicological risk evaluation, OC concentrations were consistently below the current European Maximum Residue Limits.
摘要：
我们调查了褐鳟鱼肌肉中有机氯污染物（OCs）的发生，并评估了它们对寄生虫感染的潜在调节作用。评估了消费者健康的毒理学风险，也是。鳟鱼是从西拉国家公园（卡拉布里亚地区，意大利南部）。6种非二恶英样（ndl）指示剂多氯联苯（Σ6ndl-PCBs）的浓度最高，其次是1,1,1-三氯-2,2-二(4-氯苯基)-乙烷(DDT)，二恶英样多氯联苯，六氯苯(HCB)，还有狄德林.测量脂质重量（LW），Σ6ndl-PCBs的平均值为201.9ngg-1，ΣDDTs(DDT相关化合物的总和)的平均值为100.2ngg-1，主要贡献为DDT-代谢物p，在所有样品单位中检测到的p'-DDE(平均97.6ngg-1)。在类似二恶英的同类物中，PCB118显示出最高的平均浓度（21.96ngg-1LW），并在所有样品单元中检测到。进行了肠道寄生虫对OC浓度的回归分析，控制两个潜在的混杂因素，即性和性阶段。结果表明，野生寄主-寄生虫系统中双重应激源之间存在相互作用。估计为负相关且具有统计学意义，提示OCs可能降低寄生虫感染程度。关于毒理学风险评估，OC浓度始终低于当前的欧洲最大残留限值。
