关键词: Electronic cigarette cardiovascular disease inflammation smoking sympathetic nervous system

Mesh : Humans Electronic Nicotine Delivery Systems Cardiovascular System Heart Cardiovascular Diseases / epidemiology etiology Smoking / adverse effects epidemiology

来  源:   DOI:10.1080/14779072.2023.2264179

Abstract:
UNASSIGNED: E-cigarettes have emerged as a popular alternative to traditional tobacco smoking in recent years. Despite their growing popularity, concerns have arisen regarding the cardiovascular implications of e-cigarette use.
UNASSIGNED: This narrative review aims to highlight the latest evidence on the impact of e-cigarettes on cardiovascular health.
UNASSIGNED: Numerous studies have demonstrated that e-cigarette use can lead to acute adverse cardiovascular effects. Inhalation of e-cigarette aerosols exposes users to a wide range of potentially harmful substances that have been implicated in critical pathophysiologic pathways of cardiovascular disease, namely endothelial dysfunction, oxidative stress, inflammation, sympathetic overdrive, and arterial stiffness. While long-term epidemiological studies specifically focusing on the cardiovascular effects of e-cigarettes are still relatively scarce, early evidence suggests a potential association between e-cigarette use and an increased risk of adverse cardiovascular events. However, it is essential to recognize that e-cigarettes are relatively new products, and the full extent of their long-term cardiovascular impact has not been fully elucidated. In the meantime, promoting tobacco cessation strategies that are evidence-based and regulated, along with rigorous monitoring of e-cigarette use patterns and associated health outcomes, are essential steps in safeguarding cardiovascular health in the face of this emerging public health challenge.
摘要:
近年来,电子烟已成为传统吸烟的流行替代品。尽管他们越来越受欢迎,人们对使用电子烟对心血管的影响感到担忧。
这篇叙述性综述旨在强调有关电子烟对心血管健康影响的最新证据。
大量研究表明,使用电子烟会导致急性心血管不良反应。吸入电子烟气雾剂使用户暴露于广泛的潜在有害物质,这些物质与心血管疾病的关键病理生理途径有关,即内皮功能障碍,氧化应激,炎症,交感神经超速,和动脉僵硬度.虽然专门针对电子烟对心血管影响的长期流行病学研究仍然相对稀缺,早期证据提示使用电子烟与心血管不良事件风险增加之间存在潜在关联.然而,必须认识到电子烟是相对较新的产品,其长期心血管影响的全部程度尚未完全阐明。同时,促进基于证据和监管的戒烟策略,以及对电子烟使用模式和相关健康结果的严格监测,是在面对这一新兴的公共卫生挑战时保护心血管健康的重要步骤。
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