PDF(Pubmed)
Abstract：
The periosteum is a thin layer of connective tissue covering bone. It is an essential component for bone development and fracture healing. There has been considerable research exploring the application of the periosteum in bone regeneration since the 19th century. An increasing number of studies are focusing on periosteal progenitor cells found within the periosteum and the use of hydrogels as scaffold materials for periosteum engineering and guided bone development. Here, we provide an overview of the research investigating the use of the periosteum for bone repair, with consideration given to the anatomy and function of the periosteum, the importance of the cambium layer, the culture of periosteal progenitor cells, periosteum-induced ossification, periosteal perfusion, periosteum engineering, scaffold vascularization, and hydrogel-based synthetic periostea.
摘要：
骨膜是覆盖骨的结缔组织的薄层。它是骨发育和骨折愈合的重要组成部分。自19世纪以来，已经有大量研究探索骨膜在骨再生中的应用。越来越多的研究集中在骨膜内发现的骨膜祖细胞以及使用水凝胶作为骨膜工程和引导骨发育的支架材料。这里,我们概述了研究骨膜用于骨修复的研究，考虑到骨膜的解剖结构和功能，形成层的重要性，骨膜祖细胞的培养，骨膜诱导骨化，骨膜灌注,骨膜工程,支架血管化，和基于水凝胶的合成骨膜。
