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Abstract：
Background Prediabetes is the golden period to promote, prevent, or delay diabetes mellitus (DM) conversion. This study aims to assess the risk predictors associated with prediabetes among communities without a family history of type 2 DM (T2DM). Methodology This case-control study involved 570 participants (265 prediabetes cases and the same number of age-matched controls) in Palembang, Indonesia. Each participant is willing to take fasting blood glucose, lipid profile tests, and physical examinations. Results Multivariate analysis of this study revealed that significant risk predictors identified were occupation in the informal sector (aOR = 3.28; 95% CI = 1.64-6.58; p-value = 0.001), diastolic blood pressure of 80-89 mmHg (aOR = 2.18; 95% CI = 1.35-3.52; p-value = 0.001), diastolic blood pressure of 90-99 mmHg (aOR = 2.09; 95% CI= 1.15-3.82; p-value = 0.016), with an aOR = 5.80 (95% CI= 3.71-9.05; p-value <0.001). triglyceride-glucose index was the dominant risk predictor for prediabetes. Conclusions Knowing who is most vulnerable can guide the efficient allocation of promotion and prevention resources. This finding proves essential consideration for health promoters emphasizing a healthy diet and lifestyle by maintaining diastolic pressure and triglyceride glucose (TyG) index while considering the occupation in populations without a family history of T2DM.
摘要：
背景糖尿病前期是黄金期,防止，或延迟糖尿病（DM）转换。本研究旨在评估没有2型糖尿病（T2DM）家族史的社区中与糖尿病前期相关的风险预测因子。方法学这项病例对照研究涉及570名参与者（265例糖尿病前期病例和相同数量的年龄匹配对照）在巨港，印度尼西亚。每个参与者都愿意服用空腹血糖，脂质轮廓测试，和体检。结果这项研究的多变量分析显示，确定的重要风险预测因素是非正规部门的职业（aOR=3.28；95％CI=1.64-6.58；p值=0.001），舒张压为80-89mmHg（aOR=2.18;95％CI=1.35-3.52;p值=0.001），舒张压为90-99mmHg（aOR=2.09;95％CI=1.15-3.82;p值=0.016），aOR=5.80（95%CI=3.71-9.05；p值<0.001）。甘油三酯-葡萄糖指数是糖尿病前期的主要风险预测因子.结论了解谁是最脆弱的人可以指导促进和预防资源的有效分配。这一发现证明了健康促进者通过维持舒张压和甘油三酯葡萄糖（TyG）指数来强调健康饮食和生活方式，同时考虑在没有T2DM家族史的人群中的职业。
