PDF(Pubmed)
Abstract：
UNASSIGNED: Diffusion tensor imaging (DTI) techniques are being studied as a possible diagnostic and predictive tool for the evaluation of cervical spinal cord disease. This systematic review aims to evaluate the previous DTI studies that specifically investigated the repeatability and reproducibility of DTI in the cervical spinal cord.
UNASSIGNED: A search in the PubMed, Scopus, Web of Science and Ovid electronic databases was conducted for articles published between January 1990 and February 2022 that related to the repeatability and reproducibility of DTI in evaluating the cervical spinal cord using one of the following measurements: the intraclass correlation coefficient (ICC) and/or the coefficient of variation (CV), and/or Bland-Altman (BA) differences analysis methods. DTI studies that presented full statistical analysis of repeatability and/or reproducibility tests of the cervical spinal cord in peer-reviewed full-text publications published in journals were included. Articles that included at least one of the keywords within the titles or abstracts were identified. Additional full-text papers were found by searching the citations and reference lists of related articles. This review has followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Risk of bias was evaluated with 13 criteria weighted toward methodological quality of reported studies using the QuADS assessment criteria. This assessment only included full-text articles written in English.
UNASSIGNED: A total of 11 studies were included and assessed for different characteristics, including sample size,(3-34) re-test time interval (<1 h to >3 months), test-retest reproducibility scores and acquisition method. Six studies used ICC which ranged from poor (ICC<0.37) to excellent reproducibility (ICC 0.91-0.99). Four studies reported an overall CV lower than 40% for all DTI metrics. Three studies reported the Bland-Altman (BA) differences and reported a minimum percentage showing no strong differences between repeated measurements. Quantitative analysis was not undertaken due to heterogeneity of methods. Repeatability and reproducibility measures were generally found to be good.
UNASSIGNED: This study revealed that the application of DTI and its related measures in a clinical setting in the assessment of cervical spinal cord changes is feasible and reproducible. However, cervical spinal cord DTI suffers from some existing limitations that prevent it from being routinely used in research and clinical settings.
UNASSIGNED: DTI with its parametric maps provide broad evaluation of the tissue structure of axonal white matter and are being studied as a possible diagnostic and predictive tool for the assessment of cervical spinal cord (CSC) disease.
UNASSIGNED: A search in the PubMed, Scopus, Web of Science and Ovid electronic databases was conducted for articles published between January 1990 and February 2022 that related to the repeatability and reproducibility of DTI in evaluating the cervical spinal cord using one of the following measurements: the intraclass correlation coefficient (ICC) and/or the coefficient of variation (CV), and/or Bland-Altman (BA) differences analysis methods. DTI studies that presented full statistical analysis of repeatability and/or reproducibility tests of the cervical spinal cord in peer-reviewed full-text publications published in journals were included. Articles that included at least one of the keywords within the titles or abstracts were identified. Additional full-text papers were found by searching the citations and reference lists of related articles. This review has followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Risk of bias was evaluated with 13 criteria weighted toward methodological quality of reported studies using the QuADS assessment criteria. This assessment only included full-text articles written in English.
UNASSIGNED: A total of 11 studies were included and assessed for different characteristics, including sample size,(3-34) re-test time interval (<1 h to >3 months), test-retest reproducibility scores and acquisition method. Six studies used ICC which ranged from poor (ICC<0.37) to excellent reproducibility (ICC 0.91-0.99). Four studies reported an overall CV lower than 40% for all DTI metrics. Three studies reported the Bland-Altman (BA) differences and reported a minimum percentage showing no strong differences between repeated measurements. Quantitative analysis was not undertaken due to heterogeneity of methods. Repeatability and reproducibility measures were generally found to be good.
UNASSIGNED: This study revealed that the application of DTI and its related measures in a clinical setting in the assessment of cervical spinal cord changes is feasible and reproducible. However, cervical spinal cord DTI suffers from some existing limitations that prevent it from being routinely used in research and clinical settings.
UNASSIGNED: DTI with its parametric maps provide broad evaluation of the tissue structure of axonal white matter and are being studied as a possible diagnostic and predictive tool for the assessment of cervical spinal cord (CSC) disease.
摘要：
■正在研究扩散张量成像（DTI）技术，作为评估颈脊髓疾病的可能的诊断和预测工具。本系统综述旨在评估先前的DTI研究，这些研究专门研究了DTI在颈脊髓中的可重复性和可重复性。
■在PubMed中进行搜索，Scopus,WebofScience和Ovid电子数据库是针对1990年1月至2022年2月之间发表的与DTI在使用以下测量之一评估颈脊髓的可重复性和可重复性有关的文章进行的：类内相关系数（ICC）和/或变异系数（CV），和/或Bland-Altman(BA)差异分析方法。包括DTI研究，这些研究在期刊上发表的同行评审全文出版物中对颈脊髓的可重复性和/或可重复性测试进行了完整的统计分析。确定了标题或摘要中至少包含一个关键字的文章。通过搜索相关文章的引用和参考列表，可以找到其他全文论文。本评论遵循了系统评论和荟萃分析（PRISMA）指南的首选报告项目。使用QuADS评估标准，根据13项标准对报告研究的方法学质量进行加权评估偏倚风险。此评估仅包括用英语撰写的全文文章。
■共纳入了11项研究，并评估了不同的特征，包括样本量，（3-34）重新测试时间间隔（<1小时至>3个月），复测再现性评分和获取方法。六项研究使用ICC，范围从较差（ICC<0.37）到出色的可重复性（ICC0.91-0.99）。四项研究报告所有DTI指标的总CV低于40%。三项研究报告了Bland-Altman（BA）差异，并报告了最低百分比，表明重复测量之间没有明显差异。由于方法的异质性，没有进行定量分析。通常发现重复性和再现性措施是良好的。
■这项研究表明，DTI及其相关措施在临床环境中评估颈脊髓变化是可行且可重复的。然而,颈脊髓DTI存在一些现有的局限性,使其无法在研究和临床环境中常规使用.
■DTI及其参数图提供了轴突白质组织结构的广泛评估，并正在研究作为评估颈脊髓（CSC）疾病的可能诊断和预测工具。
■在PubMed中进行搜索，Scopus,WebofScience和Ovid电子数据库是针对1990年1月至2022年2月之间发表的与DTI在使用以下测量之一评估颈脊髓的可重复性和可重复性有关的文章进行的：类内相关系数（ICC）和/或变异系数（CV），和/或Bland-Altman(BA)差异分析方法。包括DTI研究，这些研究在期刊上发表的同行评审全文出版物中对颈脊髓的可重复性和/或可重复性测试进行了完整的统计分析。确定了标题或摘要中至少包含一个关键字的文章。通过搜索相关文章的引用和参考列表，可以找到其他全文论文。本评论遵循了系统评论和荟萃分析（PRISMA）指南的首选报告项目。使用QuADS评估标准，根据13项标准对报告研究的方法学质量进行加权评估偏倚风险。此评估仅包括用英语撰写的全文文章。
■共纳入了11项研究，并评估了不同的特征，包括样本量，（3-34）重新测试时间间隔（<1小时至>3个月），复测再现性评分和获取方法。六项研究使用ICC，范围从较差（ICC<0.37）到出色的可重复性（ICC0.91-0.99）。四项研究报告所有DTI指标的总CV低于40%。三项研究报告了Bland-Altman（BA）差异，并报告了最低百分比，表明重复测量之间没有明显差异。由于方法的异质性，没有进行定量分析。通常发现重复性和再现性措施是良好的。
■这项研究表明，DTI及其相关措施在临床环境中评估颈脊髓变化是可行且可重复的。然而,颈脊髓DTI存在一些现有的局限性,使其无法在研究和临床环境中常规使用.
■DTI及其参数图提供了轴突白质组织结构的广泛评估，并正在研究作为评估颈脊髓（CSC）疾病的可能诊断和预测工具。
