Abstract：
BACKGROUND: This study aimed to detect medial meniscal posterior root tear (MMPRT) diagnostic methods with high sensitivity and specificity using dynamic ultrasonographic evaluation in patients with early knee osteoarthritis (OA) and demonstrate the usefulness of dynamic ultrasonographic medial meniscal extrusion (MME) evaluation in MMPRT diagnosis using a cutoff value.
METHODS: Between 2018 and 2020, a total of 120 patients were diagnosed with early knee OA using clinical and radiographic findings. Dynamic ultrasonographic evaluations and magnetic resonance imaging were performed in all patients, and 47 patients who had and 73 patients who did not have MMPRT were classified into the MMPRT and non-MMPRT groups, respectively. Age, sex, femorotibial angle, MME of knee extension and flexion, and MME at weight-bearing were compared between the two groups. Additionally, the sensitivity and specificity of significant ultrasonographic findings were calculated using a receiver operating characteristic (ROC) curve.
RESULTS: The MMEs under knee extension-flexion and weight-loading in the MMPRT group were significantly larger than those in the non-MMPRT group. ROC curve analysis for each ultrasonographic evaluation condition to diagnose MMPRT indicated that the sensitivity was 72-88% and the specificity was 66-85% when the cutoff values of MME under knee flexion at 0°, 90°, and weight-loading were set at 2.55 mm, 2.00 mm, and 3.55 mm, respectively. The highest sensitivity (88%) and specificity (85%) were exhibited upon > 2 mm MME at a knee flexion of 90° and were the most useful indicators for MME diagnosis.
CONCLUSIONS: Ultrasonographic MME evaluations for MMPRT diagnosis showed relatively high sensitivity and specificity in patients with early knee OA. Dynamic ultrasonographic MME evaluation may lead to appropriate additional examinations, early diagnosis, and intervention for MMPRT in patients with early knee OA.
METHODS: Between 2018 and 2020, a total of 120 patients were diagnosed with early knee OA using clinical and radiographic findings. Dynamic ultrasonographic evaluations and magnetic resonance imaging were performed in all patients, and 47 patients who had and 73 patients who did not have MMPRT were classified into the MMPRT and non-MMPRT groups, respectively. Age, sex, femorotibial angle, MME of knee extension and flexion, and MME at weight-bearing were compared between the two groups. Additionally, the sensitivity and specificity of significant ultrasonographic findings were calculated using a receiver operating characteristic (ROC) curve.
RESULTS: The MMEs under knee extension-flexion and weight-loading in the MMPRT group were significantly larger than those in the non-MMPRT group. ROC curve analysis for each ultrasonographic evaluation condition to diagnose MMPRT indicated that the sensitivity was 72-88% and the specificity was 66-85% when the cutoff values of MME under knee flexion at 0°, 90°, and weight-loading were set at 2.55 mm, 2.00 mm, and 3.55 mm, respectively. The highest sensitivity (88%) and specificity (85%) were exhibited upon > 2 mm MME at a knee flexion of 90° and were the most useful indicators for MME diagnosis.
CONCLUSIONS: Ultrasonographic MME evaluations for MMPRT diagnosis showed relatively high sensitivity and specificity in patients with early knee OA. Dynamic ultrasonographic MME evaluation may lead to appropriate additional examinations, early diagnosis, and intervention for MMPRT in patients with early knee OA.
摘要：
背景：本研究旨在通过动态超声评估早期膝骨关节炎（OA）患者，以高灵敏度和特异性检测内侧半月板后根撕裂（MMPRT）诊断方法，并证明动态超声评估内侧半月板挤压（MME）在MMPRT诊断中使用临界值的有用性。
方法：在2018年至2020年之间，共有120例患者通过临床和影像学检查被诊断为早期膝关节OA。对所有患者进行动态超声检查和磁共振成像,将47例患者和73例未进行MMPRT的患者分为MMPRT和非MMPRT组，分别。年龄,性别,股胫骨角，膝盖伸展和屈曲的MME，比较两组负重时的MME。此外,使用受试者工作特征(ROC)曲线计算有意义的超声检查结果的敏感性和特异性.
结果：MMPRT组膝关节伸屈和负重状态下的MME明显大于非MMPRT组。对每种超声评估条件诊断MMPRT的ROC曲线分析表明，当膝关节屈曲0°时，MME的临界值为72-88％，特异性为66-85％。90°,重量载荷设定为2.55毫米，2.00mm,和3.55毫米，分别。在膝关节屈曲90°时>2mm的MME表现出最高的灵敏度（88％）和特异性（85％），是MME诊断最有用的指标。
结论：在早期膝关节OA患者中，对MMPRT诊断的超声MME评估显示出相对较高的敏感性和特异性。动态超声MME评估可能会导致适当的额外检查，早期诊断,并对早期膝关节OA患者进行MMPRT的干预。
方法：在2018年至2020年之间，共有120例患者通过临床和影像学检查被诊断为早期膝关节OA。对所有患者进行动态超声检查和磁共振成像,将47例患者和73例未进行MMPRT的患者分为MMPRT和非MMPRT组，分别。年龄,性别,股胫骨角，膝盖伸展和屈曲的MME，比较两组负重时的MME。此外,使用受试者工作特征(ROC)曲线计算有意义的超声检查结果的敏感性和特异性.
结果：MMPRT组膝关节伸屈和负重状态下的MME明显大于非MMPRT组。对每种超声评估条件诊断MMPRT的ROC曲线分析表明，当膝关节屈曲0°时，MME的临界值为72-88％，特异性为66-85％。90°,重量载荷设定为2.55毫米，2.00mm,和3.55毫米，分别。在膝关节屈曲90°时>2mm的MME表现出最高的灵敏度（88％）和特异性（85％），是MME诊断最有用的指标。
结论：在早期膝关节OA患者中，对MMPRT诊断的超声MME评估显示出相对较高的敏感性和特异性。动态超声MME评估可能会导致适当的额外检查，早期诊断,并对早期膝关节OA患者进行MMPRT的干预。
