PDF(Pubmed)
Abstract：
Xanthogranulomatous pyelonephritis (XGP) is a distinct entity characterized by chronic granulomatous changes in the renal parenchyma associated with renal destruction and urinary tract abnormalities, most often from obstruction or infection in the urinary tract. We have presented the case report of a girl with fever, abdominal pain, vomiting, anorexia, and weight loss. Computed tomography of the abdomen showed multiloculated cystic lesions with calcifications and a psoas muscle abscess, which tested positive for Escherichia (E.) coli. Histopathology revealed lipid-laden macrophages, multinucleated giant cells, and fibrosis. Nephrectomy and drainage of the psoas abscess were done. XGP, although rare, should not be confused with renal tumors and should be considered in children presenting with fever and urinary tract symptoms. Early diagnosis can be reached with CT. Nephrectomy is the definitive treatment.
摘要：
黄色肉芽肿性肾盂肾炎（XGP）是一种独特的实体，其特征是肾实质的慢性肉芽肿性变化与肾脏破坏和尿路异常有关。最常来自尿路阻塞或感染。我们提交了一个发烧女孩的病例报告，腹痛,呕吐,厌食症,和减肥。腹部计算机断层扫描显示多部位囊性病变伴钙化和腰大肌脓肿，埃希氏菌检测呈阳性(E.）大肠杆菌。组织病理学显示富含脂质的巨噬细胞，多核巨细胞,和纤维化。进行肾切除术和腰大肌脓肿引流。XGP,虽然罕见，不应与肾脏肿瘤混淆，并且应在出现发烧和尿路症状的儿童中考虑。CT可早期诊断。肾切除术是决定性的治疗方法。
