Abstract：
Immune-mediated cerebellar ataxias were initially described as a clinical entity in the 1980s, and since then, an expanding body of evidence has contributed to our understanding of this topic. These ataxias encompass various etiologies, including postinfectious cerebellar ataxia, gluten ataxia, paraneoplastic cerebellar degeneration, opsoclonus-myoclonus-ataxia syndrome and primary autoimmune cerebellar ataxia. The increased permeability of the brain-blood barrier could potentially explain the vulnerability of the cerebellum to autoimmune processes. In this manuscript, our objective is to provide a comprehensive review of the most prevalent diseases within this group, emphasizing clinical indicators, pathogenesis, and current treatment approaches.
摘要：
免疫介导的小脑共济失调最初在1980年代被描述为临床实体，从那以后,越来越多的证据有助于我们对这个话题的理解。这些共济失调包括各种病因，包括感染后小脑共济失调,面筋共济失调,副肿瘤小脑变性，视阵风-肌阵风-共济失调综合征和原发性自身免疫性小脑共济失调。脑血屏障通透性的增加可能解释小脑对自身免疫过程的脆弱性。在这份手稿中,我们的目标是对该组中最常见的疾病进行全面审查，强调临床指标，发病机制，以及目前的治疗方法。
