Nine cats with presumptive idiopathic epilepsy, receiving oral PB q24h, were included in a retrospective descriptive study.
Seizure remission was achieved in 88% (8/9) of the cats and good seizure control in 12% (1/9) of the cats, treated with a mean dose of oral PB of 2.6 mg/kg q24h (range 1.4-3.8 mg/kg). No cats required an increase of their PB frequency at any time during a mean follow-up period of 3.5 years (range 1.1-8.0 years). No cats displayed side effects or issues with compliance at the last recorded follow-up.
Once-a-day administration of PB for feline epilepsy was safe and resulted in satisfactory seizure control for the nine cats included in this study. The results of this study justify exploring this topic further in larger prospective studies.
方法:九只猫患有特发性癫痫,接受口服PBq24h,纳入一项回顾性描述性研究。
结果:88%(8/9)的猫实现了癫痫缓解,12%(1/9)的猫实现了良好的癫痫控制,口服PB的平均剂量为2.6mg/kgq24h(范围为1.4-3.8mg/kg)。在平均3.5年(范围1.1-8.0年)的随访期内,没有猫需要在任何时候增加其PB频率。在最后一次记录的随访中,没有猫显示副作用或依从性问题。
结论:每天一次给予PB治疗猫科动物癫痫是安全的,并且对于本研究中的9只猫来说,癫痫发作得到了令人满意的控制。这项研究的结果证明了在更大的前瞻性研究中进一步探索这一主题。