Abstract：
Neck hybrid schwannoma/neurofibromas are uncommon and classified as peripheral nerve sheath tumors (PNSTs). PNSTs develop from soft tissues, of which schwannoma, perineurioma, and neurofibroma are the most common. Hybrid PNSTs consist of more than 1 type of PNST, such as hybrid schwannoma/neurofibromas. The exact epidemiology and pathogenesis of these tumors are still largely unknown because of the limited studies on this topic. Such tumors can spread over the soft tissues, although most cases reported involve the subcutaneous layer or dermis. Some studies have suggested that hybrid schwannoma/neurofibromas may be associated with neurofibromatosis. We present a case of a 51-year-old female patient with a neck hybrid schwannoma/neurofibroma diagnosed by histopathology and immunohistochemistry. The patient was referred to the neurology department for neurofibromatosis screening, which reported negative results. After 12 months, the patient showed no evidence of tumor recurrence.
摘要：
颈部混合神经鞘瘤/神经纤维瘤并不常见，分类为周围神经鞘瘤（PNSTs）。PNST从软组织发展而来,其中神经鞘瘤，神经鞘瘤,和神经纤维瘤是最常见的。混合PNST由1种以上的PNST组成,如混合神经鞘瘤/神经纤维瘤。由于对该主题的研究有限，这些肿瘤的确切流行病学和发病机理仍在很大程度上未知。这种肿瘤可以扩散到软组织上，尽管大多数病例报道涉及皮下层或真皮。一些研究表明，混合神经鞘瘤/神经纤维瘤可能与神经纤维瘤病有关。我们介绍了一例51岁的女性患者，通过组织病理学和免疫组织化学诊断为颈部混合神经鞘瘤/神经纤维瘤。患者被转诊到神经内科进行神经纤维瘤病筛查，报告阴性结果。12个月后,患者没有肿瘤复发的证据.
