PDF(Pubmed)
Abstract：
Over the last decade, we were facing medical struggle by the emergence of multi-resistant bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA). MRSA infections are still causing a growing global concern due to the rapid adaptive multidrug resistance to conventional antibiotics in human, community and veterinary medicine. Here we provide an overview about MRSA epidemiology, transmission and alternative potential treatments particularly new discovered phytochemicals with biological activity. In this narrative review, bibliographic data was collected from literature search databases: Google Scholar, web of science and PubMed/MEDLINE during recent years (2016 to 2021). MRSA is responsible of wide spectrum life threatening infections such us septicemia, endocarditis, and wound infections. It has epidemic potential in hospitals, that is responsible of most nosocomial infections leading to mortality and constitute a real burden for the healthcare systems. Effective preventive strategies for management of MRSA are highly required moreover, the identification and development of novel drugs or active biomolecules through phytochemicals are time challenging to face new resistant strains.
摘要：
在过去的十年里，我们面临着多重耐药细菌的出现，尤其是耐甲氧西林金黄色葡萄球菌（MRSA）。由于人类对常规抗生素的快速适应性多药耐药性，MRSA感染仍在引起全球越来越多的关注。社区和兽医。在这里，我们提供有关MRSA流行病学的概述，传播和替代潜在的治疗方法，特别是新发现的具有生物活性的植物化学物质。在这篇叙述性评论中，书目数据来自文献检索数据库：谷歌学者，近年来(2016年至2021年)的科学和PubMed/MEDLINE网络。MRSA是广谱威胁生命的感染，如美国败血症，心内膜炎,和伤口感染。它在医院有流行的潜力，这是大多数医院感染导致死亡的原因，并构成了医疗保健系统的真正负担。此外，非常需要有效的预防策略来管理MRSA，通过植物化学物质鉴定和开发新型药物或活性生物分子是面对新耐药菌株的时间挑战。
