PDF(Pubmed)
Abstract：
UNASSIGNED: Negative pressure wound therapy (NPWT) is commonly used in wound management of both acute and chronic wounds. As wound care has advanced, traditional NPWT has evolved to include instillation and dwell time (NPWTi-d). To better understand the potential clinical benefits of NPWTi-d, an assessment of the available literature focusing on NPWTi-d mechanisms of action in wound management was conducted. Methods. A literature search was performed for abstracts and articles published between 2010 and 2023. Published studies in English that discussed NPWTi-d mechanisms of action and included a study population larger than 10 patients were examined.
UNASSIGNED: A total of 1878 articles were identified through the literature search. After removal of duplicates and article reviews, 29 studies discussing the mechanisms of action for NPWTi-d were found. Study types included case series (n = 20), comparative study (n = 6), randomized controlled trial (n = 2), and retrospective study (n = 1). These studies included approximately 1108 patients who received NPWTi-d as part of a wound care treatment plan. NPWTi-d use was associated with improved wound and clinical outcomes through wound cleansing, removal of exudate and infectious materials, and promotion of granulation tissue development.
UNASSIGNED: The mechanisms of action for NPWTi-d helps provide wound management through wound cleansing, removal of exudate and infectious materials, and promoting the development of granulation tissue. Additional studies are warranted to fully assess the potential clinical and health economic benefits of NPWTi-d use.
UNASSIGNED: A total of 1878 articles were identified through the literature search. After removal of duplicates and article reviews, 29 studies discussing the mechanisms of action for NPWTi-d were found. Study types included case series (n = 20), comparative study (n = 6), randomized controlled trial (n = 2), and retrospective study (n = 1). These studies included approximately 1108 patients who received NPWTi-d as part of a wound care treatment plan. NPWTi-d use was associated with improved wound and clinical outcomes through wound cleansing, removal of exudate and infectious materials, and promotion of granulation tissue development.
UNASSIGNED: The mechanisms of action for NPWTi-d helps provide wound management through wound cleansing, removal of exudate and infectious materials, and promoting the development of granulation tissue. Additional studies are warranted to fully assess the potential clinical and health economic benefits of NPWTi-d use.
摘要：
负压伤口治疗(NPWT)通常用于急性和慢性伤口的伤口处理。随着伤口护理的进展，传统的NPWT已经发展为包括滴注和停留时间(NPWTi-d)。为了更好地了解NPWTi-d的潜在临床益处，我们对现有文献进行了评估,重点是NPWTi-d在伤口处理中的作用机制.方法。对2010年至2023年之间发表的摘要和文章进行了文献检索。以英语发表的研究，讨论了NPWTi-d的作用机制，并检查了大于10名患者的研究人群。
■通过文献检索，共鉴定出1878篇文献。删除重复项和文章评论后，发现了29项讨论NPWTi-d作用机制的研究。研究类型包括病例系列(n=20)，比较研究(n=6)，随机对照试验（n=2），和回顾性研究（n=1）。这些研究包括大约1108名接受NPWTi-d作为伤口护理治疗计划的一部分的患者。NPWTi-d的使用与伤口清洁改善伤口和临床结果相关，去除渗出物和感染性物质，促进肉芽组织发育。
■NPWTi-d的作用机制有助于通过伤口清洁提供伤口管理，去除渗出物和感染性物质，促进肉芽组织的发育。有必要进行其他研究，以充分评估使用NPWTi-d的潜在临床和健康经济效益。
■通过文献检索，共鉴定出1878篇文献。删除重复项和文章评论后，发现了29项讨论NPWTi-d作用机制的研究。研究类型包括病例系列(n=20)，比较研究(n=6)，随机对照试验（n=2），和回顾性研究（n=1）。这些研究包括大约1108名接受NPWTi-d作为伤口护理治疗计划的一部分的患者。NPWTi-d的使用与伤口清洁改善伤口和临床结果相关，去除渗出物和感染性物质，促进肉芽组织发育。
■NPWTi-d的作用机制有助于通过伤口清洁提供伤口管理，去除渗出物和感染性物质，促进肉芽组织的发育。有必要进行其他研究，以充分评估使用NPWTi-d的潜在临床和健康经济效益。
