PDF(Pubmed)
Abstract：
Urachal adenocarcinoma (UA) represents a rare subset of bladder tumors involving a urachal remnant. Incidental gross hematuria is often the only presenting symptom, with patients often presenting late in their course, thereby imparting an overall poor prognosis. Although there are prior case reports, there is little literature reported and no standardized treatment guidelines. We report a case of a middle-aged male who presented with incidental gross hematuria after a fall. Workup indicated the presence of a calcified bladder dome mass and pathology reported a primary urachal adenocarcinoma with pelvic nodal involvement. Patient underwent surgical resection and subsequent adjuvant, systemic chemotherapy regimen with leucovorin, fluorouracil, and oxaliplatin (FOLFOX). We hope to bring greater awareness to this rare cause of bladder malignancy.
摘要：
Urachal腺癌（UA）代表罕见的膀胱肿瘤子集，涉及脐尿管残留。偶发性肉眼血尿通常是唯一的症状，患者经常在病程后期出现，从而赋予整体不良预后。虽然以前有病例报告,几乎没有文献报道,也没有标准化的治疗指南.我们报告了一例中年男性，跌倒后出现偶然的肉眼血尿。检查显示存在钙化的膀胱圆顶肿块，病理报告原发性脐尿管腺癌伴盆腔淋巴结受累。患者接受了手术切除和随后的辅助治疗，用亚叶酸的全身化疗方案，氟尿嘧啶,和奥沙利铂（FOLFOX）。我们希望对膀胱恶性肿瘤的这种罕见原因有更多的认识。
