Abstract：
BACKGROUND: As guidelines endorse the use of computed tomography (CT) for examining coronary artery disease (CAD), it is important to compare the advantages and disadvantages of the novel photon counting detector CT (PCD-CT) technology with the established energy integrating detector CT (EID-CT).
OBJECTIVE: To compare the image quality of coronary computed tomography angiography (CCTA) and the Agatston scores (AS) derived from EID-CT and PCD-CT.
METHODS: In this prospective observational study, 28 patients underwent clinical calcium score and CCTA scans on an EID-CT and a PCD-CT scanner. CCTA images were qualitatively analyzed by five observers using visual grading characteristics. The correlation and agreement of the AS were assessed using Spearman\'s rank correlation and Bland-Altman plots.
RESULTS: This qualitative analyses demonstrated a high fraction of \"good\" or \"excellent\" ratings for the image criteria in both CT systems. The sharpness of the distal lumen and image quality regarding motion artifacts were rated significantly higher for EID-CT (P < 0.05). However, the sharpness of coronary calcification was rated significantly higher for PCD-CT (P < 0.05). Spearman\'s rank correlation and Bland-Altman plots showed good correlation (P = 0.95) and agreement regarding the AS between EID-CT and PCD-CT.
CONCLUSIONS: Both CT systems exhibited high CCTA image quality. The sharpness of calcifications was rated significantly higher for PCD-CT. A good correlation was observed between the AS derived from the two systems.
OBJECTIVE: To compare the image quality of coronary computed tomography angiography (CCTA) and the Agatston scores (AS) derived from EID-CT and PCD-CT.
METHODS: In this prospective observational study, 28 patients underwent clinical calcium score and CCTA scans on an EID-CT and a PCD-CT scanner. CCTA images were qualitatively analyzed by five observers using visual grading characteristics. The correlation and agreement of the AS were assessed using Spearman\'s rank correlation and Bland-Altman plots.
RESULTS: This qualitative analyses demonstrated a high fraction of \"good\" or \"excellent\" ratings for the image criteria in both CT systems. The sharpness of the distal lumen and image quality regarding motion artifacts were rated significantly higher for EID-CT (P < 0.05). However, the sharpness of coronary calcification was rated significantly higher for PCD-CT (P < 0.05). Spearman\'s rank correlation and Bland-Altman plots showed good correlation (P = 0.95) and agreement regarding the AS between EID-CT and PCD-CT.
CONCLUSIONS: Both CT systems exhibited high CCTA image quality. The sharpness of calcifications was rated significantly higher for PCD-CT. A good correlation was observed between the AS derived from the two systems.
摘要：
背景：由于指南认可使用计算机断层扫描（CT）检查冠状动脉疾病（CAD），比较新型光子计数探测器CT（PCD-CT）技术与现有能量积分探测器CT（EID-CT）的优缺点是很重要的。
目的：比较来自EID-CT和PCD-CT的冠状动脉计算机断层扫描血管造影（CCTA）和Agatston评分（AS）的图像质量。
方法：在这项前瞻性观察研究中，28例患者在EID-CT和PCD-CT扫描仪上接受了临床钙评分和CCTA扫描。五名观察者使用视觉分级特征对CCTA图像进行了定性分析。使用Spearman的等级相关性和Bland-Altman图评估AS的相关性和一致性。
结果：这些定性分析表明，两种CT系统的图像标准都有很高的“良好”或“优秀”评级。对于EID-CT，远端管腔的清晰度和有关运动伪影的图像质量被评估为显着更高（P<0.05）。然而,PCD-CT显示冠状动脉钙化锐度明显增高(P<0.05)。Spearman的等级相关性和Bland-Altman图显示了EID-CT和PCD-CT之间AS的良好相关性（P=0.95）和一致性。
结论：两种CT系统均表现出高CCTA图像质量。对于PCD-CT，钙化的清晰度被评为明显更高。在来自两个系统的AS之间观察到良好的相关性。
目的：比较来自EID-CT和PCD-CT的冠状动脉计算机断层扫描血管造影（CCTA）和Agatston评分（AS）的图像质量。
方法：在这项前瞻性观察研究中，28例患者在EID-CT和PCD-CT扫描仪上接受了临床钙评分和CCTA扫描。五名观察者使用视觉分级特征对CCTA图像进行了定性分析。使用Spearman的等级相关性和Bland-Altman图评估AS的相关性和一致性。
结果：这些定性分析表明，两种CT系统的图像标准都有很高的“良好”或“优秀”评级。对于EID-CT，远端管腔的清晰度和有关运动伪影的图像质量被评估为显着更高（P<0.05）。然而,PCD-CT显示冠状动脉钙化锐度明显增高(P<0.05)。Spearman的等级相关性和Bland-Altman图显示了EID-CT和PCD-CT之间AS的良好相关性（P=0.95）和一致性。
结论：两种CT系统均表现出高CCTA图像质量。对于PCD-CT，钙化的清晰度被评为明显更高。在来自两个系统的AS之间观察到良好的相关性。
