PDF(Pubmed)
Abstract：
Postpubertal testicular teratoma exhibits malignant biological behavior and has metastatic potential. We report a case of a 17-year-old patient diagnosed with postpubertal testicular teratoma with massive retroperitoneal metastasis. The pathological examination revealed a mature teratoma without any other components. However, the patient had a significantly increased level of AFP, and 18F-FDG PET/CT showed the retroperitoneal metastasis had increased FDG uptake, with a SUVmax of 15.6, suggesting the coexistence of other germ cell tumor components, and the patient might have a poor prognosis. After resection of the retroperitoneal tumor, PET/CT further revealed multiple abdominal and pelvic metastases, with a SUVmax of 22.5. Therefore, the patient received a cycle of chemotherapy and follow-up PET/CT imaging showed the achievement of complete metabolic response after the treatment. In this case, PET/CT played a crucial role in detecting metastasis, compensating for the limitations of pathological sampling, thus establishing a definitive diagnosis and predicting prognosis. And it was evident that PET/CT also has the advantage of evaluating therapeutic efficacy.
摘要：
青春期后睾丸畸胎瘤表现出恶性生物学行为，并具有转移潜力。我们报告了一例17岁的患者，诊断为青春期后睾丸畸胎瘤并伴有大量腹膜后转移。病理检查显示成熟的畸胎瘤，没有任何其他成分。然而,患者的AFP水平显着升高，18F-FDGPET/CT显示腹膜后转移有FDG摄取增加，SUVmax为15.6，表明其他生殖细胞肿瘤成分共存，患者的预后可能较差.腹膜后肿瘤切除后,PET/CT进一步显示腹部和盆腔多发转移瘤，SUVmax为22.5。因此,患者接受了一个周期的化疗,随访PET/CT显像显示治疗后代谢完全缓解.在这种情况下,PET/CT在检测转移瘤、弥补病理取样的局限性，从而建立明确的诊断和预测预后。很明显，PET/CT也具有评估治疗效果的优势。
