PDF(Pubmed)
Abstract：
UNASSIGNED: To develop and validate an oral anticoagulant knowledge tool for Chinese-speaking patients treated with warfarin or direct oral anticoagulants (DOACs) in Hong Kong.
UNASSIGNED: This pilot validation study consisted of the following three phases: (1) the development of a knowledge tool and content validity assessment; (2) a pilot study of 200 participants, consisting of 100 patients taking warfarin or DOACs, 50 pharmacists, and 50 members of the general public; and (3) known-group validity and reliability assessments.
UNASSIGNED: A 19-item \"Chinese Oral Anticoagulants Knowledge Tool (C-OAKT)\" was developed with a scale content validity index of 0.95. The mean score for known-group validity was significantly higher in the pharmacist group than the patient groups, and the patient groups scored significantly higher than the general public (mean ± standard deviation [SD] = 90.00 ± 7.11 vs. 51.55 ± 17.49 vs. 19.0 ± 15.42, respectively; p < 0.001). The mean score was higher for patients who attended a pharmacist-managed anticoagulant therapy management clinic (PAC) than for non-PAC patients (mean ± SD = 56.80 ± 13.60 vs. 46.30 ± 9.43; p = 0.004). An analysis of internal consistency showed a Cronbach\'s alpha value of 0.86.
UNASSIGNED: The results of the pilot validation study suggested that the C-OAKT is a valid and reliable instrument for assessing patients\' knowledge of oral anticoagulants in ambulatory care settings.
UNASSIGNED: This is the first validated Chinese version of an anticoagulant knowledge assessment tool. This tool will be utilized in public hospitals in Hong Kong, and will facilitate future research exploring the relationship between anticoagulant knowledge and patient-related outcomes.
UNASSIGNED: This pilot validation study consisted of the following three phases: (1) the development of a knowledge tool and content validity assessment; (2) a pilot study of 200 participants, consisting of 100 patients taking warfarin or DOACs, 50 pharmacists, and 50 members of the general public; and (3) known-group validity and reliability assessments.
UNASSIGNED: A 19-item \"Chinese Oral Anticoagulants Knowledge Tool (C-OAKT)\" was developed with a scale content validity index of 0.95. The mean score for known-group validity was significantly higher in the pharmacist group than the patient groups, and the patient groups scored significantly higher than the general public (mean ± standard deviation [SD] = 90.00 ± 7.11 vs. 51.55 ± 17.49 vs. 19.0 ± 15.42, respectively; p < 0.001). The mean score was higher for patients who attended a pharmacist-managed anticoagulant therapy management clinic (PAC) than for non-PAC patients (mean ± SD = 56.80 ± 13.60 vs. 46.30 ± 9.43; p = 0.004). An analysis of internal consistency showed a Cronbach\'s alpha value of 0.86.
UNASSIGNED: The results of the pilot validation study suggested that the C-OAKT is a valid and reliable instrument for assessing patients\' knowledge of oral anticoagulants in ambulatory care settings.
UNASSIGNED: This is the first validated Chinese version of an anticoagulant knowledge assessment tool. This tool will be utilized in public hospitals in Hong Kong, and will facilitate future research exploring the relationship between anticoagulant knowledge and patient-related outcomes.
摘要：
■为在香港接受华法林或直接口服抗凝剂（DOAC）治疗的华法林患者开发和验证口服抗凝剂知识工具。
■这项试点验证研究包括以下三个阶段：（1）知识工具和内容有效性评估的开发；（2）200名参与者的试点研究，包括100名服用华法林或DOAC的患者，50名药剂师,和50名公众成员；(3)已知群体有效性和可靠性评估。
■开发了19项“中国口服抗凝剂知识工具（C-OAKT）”，量表内容效度指数为0.95。药剂师组的已知组有效性的平均得分明显高于患者组，患者组得分明显高于一般公众(平均值±标准差[SD]=90.00±7.11vs.51.55±17.49vs.分别为19.0±15.42；p<0.001）。参加药剂师管理的抗凝治疗管理诊所（PAC）的患者的平均得分高于非PAC患者（平均±SD=56.80±13.60vs.46.30±9.43；p=0.004）。内部一致性分析表明Cronbach的α值为0.86。
■初步验证研究的结果表明，C-OAKT是一种有效且可靠的工具，可用于评估患者在非卧床护理环境中对口服抗凝药的了解。
■这是第一个经过验证的中文版本的抗凝知识评估工具。这个工具会在本港的公立医院使用,并将促进未来研究探索抗凝知识与患者相关结局之间的关系。
■这项试点验证研究包括以下三个阶段：（1）知识工具和内容有效性评估的开发；（2）200名参与者的试点研究，包括100名服用华法林或DOAC的患者，50名药剂师,和50名公众成员；(3)已知群体有效性和可靠性评估。
■开发了19项“中国口服抗凝剂知识工具（C-OAKT）”，量表内容效度指数为0.95。药剂师组的已知组有效性的平均得分明显高于患者组，患者组得分明显高于一般公众(平均值±标准差[SD]=90.00±7.11vs.51.55±17.49vs.分别为19.0±15.42；p<0.001）。参加药剂师管理的抗凝治疗管理诊所（PAC）的患者的平均得分高于非PAC患者（平均±SD=56.80±13.60vs.46.30±9.43；p=0.004）。内部一致性分析表明Cronbach的α值为0.86。
■初步验证研究的结果表明，C-OAKT是一种有效且可靠的工具，可用于评估患者在非卧床护理环境中对口服抗凝药的了解。
■这是第一个经过验证的中文版本的抗凝知识评估工具。这个工具会在本港的公立医院使用,并将促进未来研究探索抗凝知识与患者相关结局之间的关系。
