PDF(Pubmed)
Abstract：
BACKGROUND: Apical hypertrophic cardiomyopathy (AHCM) is a subtype of hypertrophic cardiomyopathy. Due to its location, the thickening of the left ventricular apex can be missed on echocardiography. Giant negative T waves (GNTs) in left-sided chest leads are the hallmark electrocardiogram (ECG) change of AHCM.
METHODS: The first patient was a 68-year-old woman complaining of recurrent chest tightness persisting for more than 3 years. The second was a 59-year-old man complaining of spasmodic chest tightness persisting for more than 2 years. The third was a 55-year-old woman complaining of recurrent chest pain persisting for 4 mo. In all three cases, GNTs were observed several years prior to apical cardiac hypertrophy after other causes of T-wave inversion were ruled out.
CONCLUSIONS: Electrophysiological abnormalities of AHCM appear earlier than structural abnormalities, confirming the early predictive value of ECG for AHCM.
METHODS: The first patient was a 68-year-old woman complaining of recurrent chest tightness persisting for more than 3 years. The second was a 59-year-old man complaining of spasmodic chest tightness persisting for more than 2 years. The third was a 55-year-old woman complaining of recurrent chest pain persisting for 4 mo. In all three cases, GNTs were observed several years prior to apical cardiac hypertrophy after other causes of T-wave inversion were ruled out.
CONCLUSIONS: Electrophysiological abnormalities of AHCM appear earlier than structural abnormalities, confirming the early predictive value of ECG for AHCM.
摘要：
背景：心尖肥厚型心肌病（AHCM）是肥厚型心肌病的一种亚型。由于它的位置,左心室心尖增厚可在超声心动图检查中遗漏。左侧胸导联中的巨大负T波（GNTs）是AHCM的标志性心电图（ECG）变化。
方法：首例患者是一名68岁女性，主诉复发性胸闷持续3年以上。第二位是一名59岁的男子，抱怨痉挛性胸闷持续超过2年。第三名是一名55岁的妇女，抱怨反复发作的胸痛持续了4个月。在这三种情况下，在排除了其他T波倒置原因后，在心尖心肌肥大之前几年观察到了GNT。
结论：AHCM的电生理异常比结构异常更早出现，证实心电图对AHCM的早期预测价值。
方法：首例患者是一名68岁女性，主诉复发性胸闷持续3年以上。第二位是一名59岁的男子，抱怨痉挛性胸闷持续超过2年。第三名是一名55岁的妇女，抱怨反复发作的胸痛持续了4个月。在这三种情况下，在排除了其他T波倒置原因后，在心尖心肌肥大之前几年观察到了GNT。
结论：AHCM的电生理异常比结构异常更早出现，证实心电图对AHCM的早期预测价值。
