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Abstract：
Lemierre\'s syndrome is a rare, life-threatening complication of an acute oropharyngeal infection. It is generally characterised by pharyngitis secondary to Fusobacterium necrophorum, causing thrombophlebitis of the internal jugular vein and sepsis, with subsequent formation of septic emboli that can rapidly spread to different organ sites. The condition is associated with high mortality if treatment with antibiotics is delayed, and recent evidence suggests that patients are at significant risk of in-hospital morbidity and long-term neurological sequelae. Although it is agreed that antibiotics are the mainstay of treatment, there is currently no consensus on the use of anticoagulation in the condition. This review article aims to summarise our current understanding of Lemierre\'s syndrome with regard to its definition, epidemiology, microbiology, presentation, diagnosis, and treatment.
摘要：
Lemierre综合征是一种罕见的,急性口咽感染的危及生命的并发症。它通常以继发于坏死梭杆菌的咽炎为特征，引起颈内静脉血栓性静脉炎和败血症，随后形成脓毒性栓子，可以迅速扩散到不同的器官部位。如果延迟使用抗生素治疗，这种情况与高死亡率有关，最近的证据表明，患者在院内发病和长期神经系统后遗症的风险很大。尽管人们一致认为抗生素是治疗的主要手段，目前对于在这种情况下使用抗凝药物尚无共识。这篇综述文章旨在总结我们目前对Lemierre综合征定义的理解，流行病学,微生物学,介绍,诊断,和治疗。
