Abstract：
Molluscum contagiosum (MC) is a contagious infection that, although benign, can become an aesthetic burden and lead to other opportunistic infections, secondary dermatitis, and self-isolation. Currently, several treatment options are available for MC, including the newly investigated nitric oxide-releasing berdazimer gel, leading this review to evaluate randomized controlled trials (RCT) comparing berdazimer gel with a vehicle for treating MC. The meta-analysis included three reports and four RCT involving 1854 patients, with 1106 (59.6%) randomized to receive berdazimer. Our findings suggest that berdazimer is effective in the management of MC lesions, but the increased clearance of lesions and reduction of scarring must be weighed against the potential for topical adverse effects, particularly when considering the use of this therapy in pediatric patients.
摘要：
传染性软疣（MC）是一种传染性感染，虽然是良性的，可能会成为美学负担并导致其他机会性感染，继发性皮炎,和自我隔离。目前,MC有几种治疗选择，包括新研究的释放一氧化氮的Berdazimer凝胶，引导这篇综述评估比较berdazimer凝胶与载体治疗MC的随机对照试验（RCT）。荟萃分析包括3份报告和4份RCT，涉及1854例患者，1106例（59.6%）随机接受贝达西默治疗。我们的研究结果表明，berdazimer是有效的管理MC病变，但是，必须权衡病灶清除的增加和瘢痕形成的减少与潜在的局部不良反应，特别是当考虑在儿科患者中使用这种疗法时。
