关键词: anti-skin disorders ginsenosides protopanaxadiol type protopanaxatriols type skin aging

来  源:   DOI:10.1016/j.jgr.2023.04.005   PDF(Pubmed)

Abstract:
Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play anti-aging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.
摘要:
人参皂苷是人参的生物活性成分,具有抗衰老、抗氧化,抗炎,抗疲劳,和抗肿瘤。人参皂苷被归类为达玛恩,齐亚烯,和基于苷元结构的奥科替洛型三环三萜类化合物。基于与C-3,C-20和C-6,C-20连接的糖部分,达玛烷型分为原人参二醇(PPD)和原人参三醇(PPT)。人参皂苷对皮肤疾病的影响是值得注意的。它们通过增强免疫功能发挥抗衰老作用,抵抗黑色素的形成,抑制氧化,并提高胶原蛋白和透明质酸的浓度。因此,人参皂苷以前被广泛用于抵抗皮肤病和衰老。本文从作用机制和实验研究两方面详细阐述了人参皂苷在抗皮肤衰老过程中的作用。
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