PDF(Pubmed)
Abstract：
UNASSIGNED: Central obesity increases the risk of several diseases, including diabetes, cardiovascular disease (CVD), and cancer. However, the association between extremity obesity and mortality has not been extensively evaluated. The objective of this study was to investigate the quantitative effects of waist circumference (WC), arm circumference (AC), calf circumference (CC), and thigh circumference (TC) on all-cause mortality and CVD mortality.
UNASSIGNED: The study used data from the National Health and Nutrition Examination Survey (NHANES) sample survey from 1999 to 2006. A total of 19,735 participants were included in the study. We divided the participants into four groups (Q1-Q4) and used Q1 as a reference to compare the risk of all-cause mortality and CVD mortality in Q2-Q4. COX proportional hazard regression model was used to analyze the relationship between WC, AC, CC and TC on all-cause and CVD mortality. In addition, we conducted a stratified analysis of gender.
UNASSIGNED: After a mean follow-up of 11.8 years, we observed a total of 3,446 deaths, of which 591 were due to cardiovascular disease. The results showed that for both men and women, compared to the first group, the risk of all-cause mortality was significantly higher in the other three groups of WC and significantly lower in the other three groups of AC, CC, and TC. Similar results were observed after adjusting for confounding factors such as demographics.
UNASSIGNED: Our results show that all-cause and CVD mortality are positively associated with measures of central obesity and negatively associated with measures of extremity obesity, and that AC, CC, and TC can be used as potential tools to measure prognosis in the general population.
UNASSIGNED: The study used data from the National Health and Nutrition Examination Survey (NHANES) sample survey from 1999 to 2006. A total of 19,735 participants were included in the study. We divided the participants into four groups (Q1-Q4) and used Q1 as a reference to compare the risk of all-cause mortality and CVD mortality in Q2-Q4. COX proportional hazard regression model was used to analyze the relationship between WC, AC, CC and TC on all-cause and CVD mortality. In addition, we conducted a stratified analysis of gender.
UNASSIGNED: After a mean follow-up of 11.8 years, we observed a total of 3,446 deaths, of which 591 were due to cardiovascular disease. The results showed that for both men and women, compared to the first group, the risk of all-cause mortality was significantly higher in the other three groups of WC and significantly lower in the other three groups of AC, CC, and TC. Similar results were observed after adjusting for confounding factors such as demographics.
UNASSIGNED: Our results show that all-cause and CVD mortality are positively associated with measures of central obesity and negatively associated with measures of extremity obesity, and that AC, CC, and TC can be used as potential tools to measure prognosis in the general population.
摘要：
■中心性肥胖会增加几种疾病的风险，包括糖尿病,心血管疾病（CVD），和癌症。然而,四肢肥胖和死亡率之间的关联尚未得到广泛评估.这项研究的目的是调查腰围（WC）的定量影响，臂周长(AC),小腿周长(CC),和大腿围（TC）对全因死亡率和CVD死亡率的影响。
■该研究使用了1999年至2006年国家健康与营养检查调查（NHANES）抽样调查的数据。共有19,735名参与者被纳入研究。我们将参与者分为四组（Q1-Q4），并使用Q1作为参考比较Q2-Q4的全因死亡率和CVD死亡率的风险。采用COX比例风险回归模型分析WC、AC,CC和TC对全因和CVD死亡率的影响。此外,我们对性别进行了分层分析.
■经过11.8年的平均随访，我们观察到总共有3446人死亡，其中591是由于心血管疾病。结果显示，无论是男性还是女性，与第一组相比，其他三组WC的全因死亡风险显著较高，其他三组AC的全因死亡风险显著较低，CC,和TC。在调整了人口统计学等混杂因素后，也观察到了类似的结果。
■我们的结果表明，全因死亡率和心血管疾病死亡率与中心性肥胖指标呈正相关，与四肢肥胖指标呈负相关，那个AC,CC,TC可作为衡量一般人群预后的潜在工具。
■该研究使用了1999年至2006年国家健康与营养检查调查（NHANES）抽样调查的数据。共有19,735名参与者被纳入研究。我们将参与者分为四组（Q1-Q4），并使用Q1作为参考比较Q2-Q4的全因死亡率和CVD死亡率的风险。采用COX比例风险回归模型分析WC、AC,CC和TC对全因和CVD死亡率的影响。此外,我们对性别进行了分层分析.
■经过11.8年的平均随访，我们观察到总共有3446人死亡，其中591是由于心血管疾病。结果显示，无论是男性还是女性，与第一组相比，其他三组WC的全因死亡风险显著较高，其他三组AC的全因死亡风险显著较低，CC,和TC。在调整了人口统计学等混杂因素后，也观察到了类似的结果。
■我们的结果表明，全因死亡率和心血管疾病死亡率与中心性肥胖指标呈正相关，与四肢肥胖指标呈负相关，那个AC,CC,TC可作为衡量一般人群预后的潜在工具。
