PDF(Pubmed)
Abstract：
UNASSIGNED: The treatment of epiphora has undergone tremendous change in the past, and minimally invasive techniques are being preferred over traditional surgical options. One of them is the use of Inj Botulinum toxin, but there are very few studies that have explored its role in treating post-traumatic epiphora. This study was undertaken to find out the safety and efficacy of injection Botulinum toxin in treating epiphora due to canalicular obstruction following trauma.
UNASSIGNED: A longitudinal interventional study was done, and a total of 50 patients were recruited. All patients were subjected to Inj Botulinum toxin in the lacrimal gland (10 units). The study was done for a period of 6 months, and patients were followed up for a period of another 6 months. Changes in Munk score, Schirmer test, and tear meniscus height were considered the main outcome measures.
UNASSIGNED: In our study, there were 38 males and 12 females. The age of the patients varied from 24 yrs to 67 yrs. Inj Botulinum toxin was found to be effective in 80% (n = 40/50) of cases as they reported a reduction in watering from eyes after administration of this injection. The complication associated with this treatment was minimal in our study as four patients reported diplopia, whereas two patients developed Ptosis that resolved spontaneously within two months.
UNASSIGNED: Inj Botulinum toxin was found to be effective in epiphora caused by canalicular obstruction due to trauma. This treatment should be considered as an alternative treatment modality as it often leads to satisfactory reduction in epiphora in patients with less complications compared to surgical intervention.
UNASSIGNED: A longitudinal interventional study was done, and a total of 50 patients were recruited. All patients were subjected to Inj Botulinum toxin in the lacrimal gland (10 units). The study was done for a period of 6 months, and patients were followed up for a period of another 6 months. Changes in Munk score, Schirmer test, and tear meniscus height were considered the main outcome measures.
UNASSIGNED: In our study, there were 38 males and 12 females. The age of the patients varied from 24 yrs to 67 yrs. Inj Botulinum toxin was found to be effective in 80% (n = 40/50) of cases as they reported a reduction in watering from eyes after administration of this injection. The complication associated with this treatment was minimal in our study as four patients reported diplopia, whereas two patients developed Ptosis that resolved spontaneously within two months.
UNASSIGNED: Inj Botulinum toxin was found to be effective in epiphora caused by canalicular obstruction due to trauma. This treatment should be considered as an alternative treatment modality as it often leads to satisfactory reduction in epiphora in patients with less complications compared to surgical intervention.
摘要：
■在过去的治疗方式上发生了巨大的变化,和微创技术是首选传统的手术选择。其中之一是使用Inj肉毒杆菌毒素，但是很少有研究探讨了它在治疗创伤后泪液中的作用。进行这项研究是为了找出注射肉毒杆菌毒素在治疗创伤后泪小管阻塞引起的泪液中的安全性和有效性。
■进行了纵向介入研究，共招募了50名患者.所有患者在泪腺中接受Inj肉毒杆菌毒素(10单位)。这项研究为期6个月，并对患者进行了为期6个月的随访。Munk分数的变化,Schirmer试验,泪液半月板高度被认为是主要的结局指标。
■在我们的研究中，有38名男性和12名女性。患者的年龄从24岁到67岁不等。发现肉毒杆菌毒素在80％（n=40/50）的病例中有效，因为它们报告了在施用这种注射后眼睛的水分减少。在我们的研究中，与这种治疗相关的并发症很少，因为四名患者报告复视，而两名患者出现了在两个月内自发消退的上睑下垂。
■Inj肉毒杆菌毒素被发现对因外伤而导致的泪小管阻塞引起的溢唇有效。这种治疗应被视为一种替代治疗方式，因为与手术干预相比，它通常会导致并发症少的患者满意地减少泪滴。
■进行了纵向介入研究，共招募了50名患者.所有患者在泪腺中接受Inj肉毒杆菌毒素(10单位)。这项研究为期6个月，并对患者进行了为期6个月的随访。Munk分数的变化,Schirmer试验,泪液半月板高度被认为是主要的结局指标。
■在我们的研究中，有38名男性和12名女性。患者的年龄从24岁到67岁不等。发现肉毒杆菌毒素在80％（n=40/50）的病例中有效，因为它们报告了在施用这种注射后眼睛的水分减少。在我们的研究中，与这种治疗相关的并发症很少，因为四名患者报告复视，而两名患者出现了在两个月内自发消退的上睑下垂。
■Inj肉毒杆菌毒素被发现对因外伤而导致的泪小管阻塞引起的溢唇有效。这种治疗应被视为一种替代治疗方式，因为与手术干预相比，它通常会导致并发症少的患者满意地减少泪滴。
