PDF(Pubmed)
Abstract：
Terbutaline sulfate is a beta-adrenergic receptor agonist. More specific for B2 receptors, it is used as a bronchodilator in asthma. Its known side effects can include dizziness, tremors, and tachycardia. However, seizures are not among the commonly reported side effects. This is the case of a five-month-old girl who presented with focal seizures after the intake of terbutaline sulfate syrup. Other causes of the seizures were excluded through history and investigations, including an EEG and electrolyte panel. The seizures stopped on cessation of the terbutaline sulfate with no recurrence, leading us to believe that the focal seizures were an adverse effect of the terbutaline sulfate. A high index of suspicion for drug-related adverse effects should therefore be kept for a child with new onset focal seizures.
摘要：
硫酸特布他林是β-肾上腺素能受体激动剂。更具体的B2受体，它被用作哮喘的支气管扩张剂。其已知的副作用可能包括头晕，震颤,和心动过速.然而,癫痫发作不是常见的副作用。这是一个五个月大的女孩在摄入硫酸特布他林糖浆后出现局灶性癫痫发作的情况。通过病史和调查排除了癫痫发作的其他原因，包括脑电图和电解质面板。停止硫酸特布他林的癫痫发作，没有复发，使我们相信局灶性癫痫发作是硫酸特布他林的不利影响。因此，对于新发局灶性癫痫发作的儿童，应保持对药物相关不良反应的高度怀疑。
