Abstract：
Gastric adenocarcinoma with enteroblastic differentiation is a specific subtype of gastric cancer that is rare and highly malignant, usually presenting at an early stage with lymphovascular invasion, lymph node, and distant metastases, resulting in a poor prognosis. The pathology of this patient showed a classic tubular adenocarcinoma infiltrating into the mucosal layer, with the presence of cytoplasmic translucent tumor cells below the mucosal layer. It is noteworthy that this patient did not exhibit lymphovascular invasion, lymph node, and distant metastasis. Additionally, a large amount of calcification was observed; therefore, it remains unclear whether there exists any correlation between the two factors. To the best of our knowledge, this is the first case report demonstrating massive calcification in gastric adenocarcinoma with enteroblastic differentiation, which may have implications for future diagnosis of this rare subtype of gastric cancer.
摘要：
以肠母细胞分化的胃腺癌是胃癌的一种特殊亚型，是一种罕见且高度恶性的胃癌，通常在早期表现为淋巴管浸润，淋巴结,和远处转移，导致预后不良。该患者的病理显示典型的管状腺癌浸润到粘膜层，粘膜层下方存在细胞质半透明肿瘤细胞。值得注意的是，该患者没有表现出淋巴管浸润，淋巴结,和远处转移。此外,观察到大量钙化；因此，目前尚不清楚这两个因素之间是否存在相关性。据我们所知,这是第一例报告，证明胃腺癌伴有肠母细胞分化的大量钙化，这可能对这种罕见的胃癌亚型的未来诊断有影响。
