关键词: Deep neck space infection Lemierre’s syndrome Streptococcus anginosus

来  源:   DOI:10.1186/s12959-023-00543-x   PDF(Pubmed)

Abstract:
BACKGROUND: Lemierre\'s Syndrome is a severe medical condition that can result from oropharyngeal infection, typically caused by Fusobacterium necrophorum, leading to sepsis, internal jugular vein thrombosis, and metastatic septic emboli. However, there is limited literature on this syndrome caused by Streptococcus anginosus, and few previous cases have been reported to have deep neck space infection. We present the first case of Lemierre\'s Syndrome caused by Streptococcus anginosus with deep neck abscess.
METHODS: A 53-year-old male patient with no significant medical history presented with right neck pain after accidentally swallowing a fish bone one month ago. Laryngoscopy did not reveal any abnormalities. Five days prior to admission, the patient developed high fever. Imaging studies showed internal jugular vein thrombosis and a neck abscess surrounding the carotid artery sheath. Blood culture results were positive for Streptococcus anginosus infection, and the patient was diagnosed with Lemierre\'s syndrome. The patient underwent surgical drainage and received antibiotics and anticoagulant therapy, and had satisfactory clinical progress. He was discharged after a 16-day hospitalization.
CONCLUSIONS: Although Lemierre\'s syndrome is rare, it needs attention because it can lead to serious complications and requires timely treatment. Deep neck space infections can be life-threatening and doctors must be aware of its potential severity.
摘要:
背景:Lemierre综合征是一种严重的医疗状况,可由口咽感染引起,通常由坏死梭杆菌引起,导致败血症,颈内静脉血栓形成,和转移性脓毒性栓子.然而,关于这种由链球菌引起的综合征的文献有限,以前很少有病例报告有颈深间隙感染。我们介绍了第一例由心绞痛链球菌引起的Lemierre综合征伴颈部深部脓肿。
方法:一名无明显病史的53岁男性患者,一个月前意外吞下鱼骨后出现右侧颈部疼痛。喉镜检查未显示任何异常。入院前五天,病人发高烧。影像学检查显示颈内静脉血栓形成和颈动脉鞘周围的颈部脓肿。血培养结果阳性为链球菌感染,患者被诊断为Lemierre综合征。患者接受了手术引流,并接受了抗生素和抗凝治疗,临床进展满意。他在住院16天后出院。
结论:尽管Lemierre综合征很少见,它需要注意,因为它可能导致严重的并发症,需要及时治疗。颈部深部空间感染可能危及生命,医生必须意识到其潜在的严重程度。
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