Abstract：
BACKGROUND: To evaluate eye growth of children wearing spectacle lenses with highly aspherical lenslets (HAL), slightly aspherical lenslets (SAL) and single-vision lenses (SVL) compared to eye growth patterns in non-myopes in Wenzhou, China.
METHODS: The randomised trial had 170 myopic children (aged 8-13 years) randomly assigned to the HAL, SAL or SVL group. Normal eye growth was examined using 700 non-myopic schoolchildren (aged 7-9 years) in the Wenzhou Medical University-Essilor Progression and Onset of Myopia (WEPrOM) cohort study using logistic function models. Slow, normal and fast eye growth was defined as range of values <25th, 25th-75th and >75th percentiles, respectively.
RESULTS: The predicted upper limits of slow eye growth (25th percentile) among non-myopes aged 7-10 years and 11-13 years were 0.20-0.13 and 0.08-0.01 mm (after 2-year period; 0.37-0.33 and 0.29-0.14 mm), respectively, while the upper limits of normal eye growth (75th percentile) were 0.32-0.31 and 0.28-0.10 mm (after 2-year period; 0.58-0.55 and 0.50-0.24 mm), respectively. The 2-year trial had 157 children, 96 of whom wore their lenses full time (everyday ≥12 h/day). The mean 2-year axial length change for HAL, SAL and SVL was 0.34, 0.51 and 0.69 mm (0.28, 0.46 and 0.69 mm in full-time wear), respectively. Slow eye growth was found in 35%, 17% and 2% (44%, 29% and 3% in full-time wear); normal eye growth in 35%, 26% and 12% (44%, 32% and 9% in full-time wear) and fast eye growth in 30%, 57% and 86% (12%, 39% and 88% in full-time wear), respectively (p < 0.001).
CONCLUSIONS: The eye growth pattern in approximately 90% wearing HAL full time (compared with about 10% wearing SVL full time) was similar or slower than that of non-myopic children both after 1- and 2-year periods.
METHODS: The randomised trial had 170 myopic children (aged 8-13 years) randomly assigned to the HAL, SAL or SVL group. Normal eye growth was examined using 700 non-myopic schoolchildren (aged 7-9 years) in the Wenzhou Medical University-Essilor Progression and Onset of Myopia (WEPrOM) cohort study using logistic function models. Slow, normal and fast eye growth was defined as range of values <25th, 25th-75th and >75th percentiles, respectively.
RESULTS: The predicted upper limits of slow eye growth (25th percentile) among non-myopes aged 7-10 years and 11-13 years were 0.20-0.13 and 0.08-0.01 mm (after 2-year period; 0.37-0.33 and 0.29-0.14 mm), respectively, while the upper limits of normal eye growth (75th percentile) were 0.32-0.31 and 0.28-0.10 mm (after 2-year period; 0.58-0.55 and 0.50-0.24 mm), respectively. The 2-year trial had 157 children, 96 of whom wore their lenses full time (everyday ≥12 h/day). The mean 2-year axial length change for HAL, SAL and SVL was 0.34, 0.51 and 0.69 mm (0.28, 0.46 and 0.69 mm in full-time wear), respectively. Slow eye growth was found in 35%, 17% and 2% (44%, 29% and 3% in full-time wear); normal eye growth in 35%, 26% and 12% (44%, 32% and 9% in full-time wear) and fast eye growth in 30%, 57% and 86% (12%, 39% and 88% in full-time wear), respectively (p < 0.001).
CONCLUSIONS: The eye growth pattern in approximately 90% wearing HAL full time (compared with about 10% wearing SVL full time) was similar or slower than that of non-myopic children both after 1- and 2-year periods.
摘要：
背景：为了评估佩戴高度非球面透镜（HAL）的眼镜片的儿童的眼睛生长，与温州非近视眼的眼睛生长模式相比，微非球面透镜（SAL）和单视透镜（SVL），中国。
方法：该随机试验将170名近视儿童（8-13岁）随机分配到HAL，SAL或SVL组。在温州医科大学-Essilor进展和近视发作（WEProM）队列研究中，使用逻辑功能模型检查了700名非近视学童（7-9岁）的正常眼睛生长。慢,正常和快速的眼睛生长被定义为<25，25-75和>75百分位数，分别。
结果：在7-10岁和11-13岁的非近视患者中，眼睛缓慢生长的预测上限（第25百分位数）为0.20-0.13和0.08-0.01mm（在2年之后；0.37-0.33和0.29-0.14mm），分别,而正常眼生长的上限（第75百分位数）为0.32-0.31和0.28-0.10mm（2年后；0.58-0.55和0.50-0.24mm），分别。这项为期两年的试验有157名儿童，其中96人全职佩戴镜片（每天≥12小时/天）。HAL的平均2年轴向长度变化，SAL和SVL分别为0.34、0.51和0.69mm（全时磨损为0.28、0.46和0.69mm），分别。35％的人发现眼睛生长缓慢，17%和2%(44%，全时佩戴的29％和3％）；正常的眼睛增长35％，26%和12%(44%，全时佩戴的32％和9％）和30％的快速眼睛增长，57%和86%(12%，39%和88%的全职穿着），分别(p<0.001)。
结论：在1年和2年后，大约90％的全时佩戴HAL（约10％的全时佩戴SVL）的眼睛生长模式与非近视儿童相似或更慢。
方法：该随机试验将170名近视儿童（8-13岁）随机分配到HAL，SAL或SVL组。在温州医科大学-Essilor进展和近视发作（WEProM）队列研究中，使用逻辑功能模型检查了700名非近视学童（7-9岁）的正常眼睛生长。慢,正常和快速的眼睛生长被定义为<25，25-75和>75百分位数，分别。
结果：在7-10岁和11-13岁的非近视患者中，眼睛缓慢生长的预测上限（第25百分位数）为0.20-0.13和0.08-0.01mm（在2年之后；0.37-0.33和0.29-0.14mm），分别,而正常眼生长的上限（第75百分位数）为0.32-0.31和0.28-0.10mm（2年后；0.58-0.55和0.50-0.24mm），分别。这项为期两年的试验有157名儿童，其中96人全职佩戴镜片（每天≥12小时/天）。HAL的平均2年轴向长度变化，SAL和SVL分别为0.34、0.51和0.69mm（全时磨损为0.28、0.46和0.69mm），分别。35％的人发现眼睛生长缓慢，17%和2%(44%，全时佩戴的29％和3％）；正常的眼睛增长35％，26%和12%(44%，全时佩戴的32％和9％）和30％的快速眼睛增长，57%和86%(12%，39%和88%的全职穿着），分别(p<0.001)。
结论：在1年和2年后，大约90％的全时佩戴HAL（约10％的全时佩戴SVL）的眼睛生长模式与非近视儿童相似或更慢。
