Mesh : Humans Immunoblastic Lymphadenopathy / diagnosis complications pathology Lupus Erythematosus, Systemic / diagnosis complications Lymphoma, T-Cell / diagnosis complications pathology

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Abstract:
UNASSIGNED: This study aimed to investigate the clinical features of angioimmunoblastic T-cell lymphoma (AITL) mimicking systemic lupus erythematosus (SLE) and raise awareness about AITL among rheumatologists in order to prevent misdiagnosis and missed diagnosis. The study reports on a case of AITL mimicking SLE and provides a literature review.
UNASSIGNED: Using key words as search terms, relevant articles published in PubMed before 2022-05 were searched, and their clinical characteristics were collected and analyzed.
UNASSIGNED: The literature review retrieved six case reports, including four cases initially diagnosed with SLE and then with AITL. The other two case diagnoses were SLE and AITL, respectively. The two diseases are pathogenically associated and share some common features. The clinical manifestations of AITL are complex. The disease is closely associated with abnormal immune functions and is highly heterogeneous.
UNASSIGNED: Patients with AITL generally have a poor prognosis. Rarely do reported cases show AITL mimicking SLE. AITL should be considered during clinical practice to prevent missed diagnoses or misdiagnoses.
摘要:
本研究旨在探讨模拟系统性红斑狼疮(SLE)的血管免疫母细胞性T细胞淋巴瘤(AITL)的临床特征,并提高风湿病学家对AITL的认识,以防止误诊和漏诊。该研究报告了一例AITL模仿SLE的病例,并提供了文献综述。
使用关键词作为搜索词,搜索了2022-05年之前在PubMed上发表的相关文章,收集并分析其临床特点。
文献综述检索到6例病例报告,包括4例最初诊断为SLE,然后诊断为AITL。另外两例诊断为SLE和AITL,分别。这两种疾病在发病机制上是相关的,并且具有一些共同的特征。AITL的临床表现复杂。该疾病与免疫功能异常密切相关,并且具有高度异质性。
AITL患者通常预后不良。报道的病例很少显示AITL模仿SLE。在临床实践中应考虑AITL,以防止漏诊或误诊。
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