PDF(Pubmed)
Abstract：
Pulmonary sequestration is a rare congenital condition. It is a dysplastic lung tissue with a separate systemic blood supply and without a bronchial tree connection. The emergence of a superimposed infection can lead to its diagnosis, such as Staphylococcus aureus, Pseudomonas aeruginosa, Nocardia asteroids and Aspergillus sp pneumonia. Mycobacterium avium complex (MAC) superimposed disease is exceedingly rare. We report a case of a man in his third decade without known medical disorders presenting with a persistent cough. After an extensive microbiological workup, an MAC infection was diagnosed. An elevated carbohydrate antigen 19-9 (CA 19-9) was also noted. He was treated with antimycobacterial therapy and lobectomy resulting in clinical improvement and CA19-9 normalisation. This case illustrates the value of comprehensive microbiological investigations in patients with chronic respiratory symptoms and imaging findings that are not typical of bacterial pneumonia. Clinical studies remain needed to investigate the utility of CA 19-9 in a scoring system to guide MAC therapy.
摘要：
肺隔离症是一种罕见的先天性疾病。它是一种发育不良的肺组织，具有单独的全身血液供应，没有支气管树连接。叠加感染的出现可以导致其诊断，如金黄色葡萄球菌，铜绿假单胞菌,诺卡氏菌小行星和肺炎曲霉。鸟分枝杆菌复合体（MAC）叠加病极为罕见。我们报告了一名男子在他的第三个十年中没有已知的医学疾病表现为持续咳嗽的病例。经过广泛的微生物检查，诊断为MAC感染。还注意到升高的碳水化合物抗原19-9(CA19-9)。他接受了抗分枝杆菌治疗和肺叶切除术，导致临床改善和CA19-9正常化。此病例说明了全面的微生物学检查对患有慢性呼吸道症状和影像学发现的细菌性肺炎患者的价值。仍然需要临床研究来研究CA19-9在评分系统中的实用性以指导MAC治疗。
