Abstract：
OBJECTIVE: The effectiveness of the HiBalance training program for individuals with Parkinson disease (PD) remains debated, prompting a systematic investigation. This study aims to assess whether the HiBalance training program yields favorable outcomes on physical function and self-reported function measures in PD individuals.
METHODS: A systematic search across PubMed, Cochrane Library, Ovid, Scopus, and PEDro databases identified studies exploring HiBalance training\'s impact on physical function in idiopathic PD. Publication date restrictions were not applied. Two independent reviewers evaluated bias risk using the Cochrane Risk of Bias tool and study quality using the PEDro scale. Effect size (standardized mean difference, SMD) and heterogeneity (Higgins I2) were determined.
RESULTS: Six studies underwent qualitative analysis, with two randomized-controlled trials and one multi-center clinical trial being included in the meta-analysis. HiBalance training exhibited a significant impact on physical function (SMD = 0.49; P = 0.0003). The Mini-BESTest score and gait velocity displayed improvements with moderate-effect sizes. However, solely gait velocity showed clinical enhancement. Yet, these benefits did not remain at the 6- and 12-month follow-ups post-intervention. Self-reported function measures showed no alteration post-HiBalance training. Publication bias was absent.
CONCLUSIONS: HiBalance training led to clinically significant improvements solely in gait velocity, though these gains waned over time. The findings suggest the necessity of refining the HiBalance program to sustain positive outcomes and ensure lasting enhancements. This underscores the importance of post-HiBalance training exercise programs to maintain benefits in the long term.
UNASSIGNED: The protocol of this review and meta-analysis was registered at PROSPERO (CRD42022325649). Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022325649 .
METHODS: A systematic search across PubMed, Cochrane Library, Ovid, Scopus, and PEDro databases identified studies exploring HiBalance training\'s impact on physical function in idiopathic PD. Publication date restrictions were not applied. Two independent reviewers evaluated bias risk using the Cochrane Risk of Bias tool and study quality using the PEDro scale. Effect size (standardized mean difference, SMD) and heterogeneity (Higgins I2) were determined.
RESULTS: Six studies underwent qualitative analysis, with two randomized-controlled trials and one multi-center clinical trial being included in the meta-analysis. HiBalance training exhibited a significant impact on physical function (SMD = 0.49; P = 0.0003). The Mini-BESTest score and gait velocity displayed improvements with moderate-effect sizes. However, solely gait velocity showed clinical enhancement. Yet, these benefits did not remain at the 6- and 12-month follow-ups post-intervention. Self-reported function measures showed no alteration post-HiBalance training. Publication bias was absent.
CONCLUSIONS: HiBalance training led to clinically significant improvements solely in gait velocity, though these gains waned over time. The findings suggest the necessity of refining the HiBalance program to sustain positive outcomes and ensure lasting enhancements. This underscores the importance of post-HiBalance training exercise programs to maintain benefits in the long term.
UNASSIGNED: The protocol of this review and meta-analysis was registered at PROSPERO (CRD42022325649). Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022325649 .
摘要：
目标：HiBalance训练计划对帕金森病（PD）患者的有效性仍存在争议，进行系统的调查。这项研究旨在评估HiBalance训练计划是否对PD个体的身体功能和自我报告的功能指标产生有利的结果。
方法：跨PubMed的系统搜索，科克伦图书馆,奥维德,Scopus,和PEDro数据库确定了探索HiBalance训练对特发性PD身体功能影响的研究。未应用发布日期限制。两名独立评审员使用Cochrane偏差风险工具评估偏倚风险，并使用PEDro量表评估研究质量。效应大小(标准化平均差，确定了SMD）和异质性（希金斯I2）。
结果：六项研究进行了定性分析，两项随机对照试验和一项多中心临床试验纳入荟萃分析.HiBalance训练对身体功能有显著影响(SMD=0.49;P=0.0003)。Mini-BESTest评分和步态速度显示出中等效果大小的改善。然而,仅步态速度显示临床增强。然而，在干预后的6个月和12个月随访中,这些获益并未保持.自我报告的功能指标显示HiBalance培训后没有变化。不存在出版偏倚。
结论：HiBalance训练导致仅在步态速度方面的临床显着改善，尽管这些收益随着时间的推移而减弱。研究结果表明，有必要完善HiBalance计划，以维持积极成果并确保持久的增强。这强调了HiBalance后训练锻炼计划对长期维持收益的重要性。
■本综述和荟萃分析的方案在PROSPERO（CRD42022325649）注册。可从以下网址获得：https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42022325649。
方法：跨PubMed的系统搜索，科克伦图书馆,奥维德,Scopus,和PEDro数据库确定了探索HiBalance训练对特发性PD身体功能影响的研究。未应用发布日期限制。两名独立评审员使用Cochrane偏差风险工具评估偏倚风险，并使用PEDro量表评估研究质量。效应大小(标准化平均差，确定了SMD）和异质性（希金斯I2）。
结果：六项研究进行了定性分析，两项随机对照试验和一项多中心临床试验纳入荟萃分析.HiBalance训练对身体功能有显著影响(SMD=0.49;P=0.0003)。Mini-BESTest评分和步态速度显示出中等效果大小的改善。然而,仅步态速度显示临床增强。然而，在干预后的6个月和12个月随访中,这些获益并未保持.自我报告的功能指标显示HiBalance培训后没有变化。不存在出版偏倚。
结论：HiBalance训练导致仅在步态速度方面的临床显着改善，尽管这些收益随着时间的推移而减弱。研究结果表明，有必要完善HiBalance计划，以维持积极成果并确保持久的增强。这强调了HiBalance后训练锻炼计划对长期维持收益的重要性。
■本综述和荟萃分析的方案在PROSPERO（CRD42022325649）注册。可从以下网址获得：https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42022325649。
