Abstract：
UNASSIGNED: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.
UNASSIGNED: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.
UNASSIGNED: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.
UNASSIGNED: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.
UNASSIGNED: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.
UNASSIGNED: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.
UNASSIGNED: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.
摘要：
■我们旨在阐明用于人工心脏瓣膜的热解碳的微观结构对其流体动力学性能的影响。
■随机选择GKS23和29A的双叶机械瓣膜。根据ISO5840，平均跨瓣压(MPG)，反流分数（RF），评估瓣膜有效孔口面积(EOA)。然后，通过在小叶表面进行激光蚀刻来构建平行凹槽图案，和阀门再次进行相同的测试。
■与以2、3.5、5和7L/min图案化之前相比，两种规格的阀门的MPG更高，23年的EOA更大，但在29A中更小，RF与EOA相反。在5升/分钟时，在45bpm下蚀刻后,两种规格中的RF都较低。然而，在70bpm时，23A的射频下降，在29A增加。
■小叶表面的平行凹槽图案影响瓣膜假体的血液动力学性能。
■随机选择GKS23和29A的双叶机械瓣膜。根据ISO5840，平均跨瓣压(MPG)，反流分数（RF），评估瓣膜有效孔口面积(EOA)。然后，通过在小叶表面进行激光蚀刻来构建平行凹槽图案，和阀门再次进行相同的测试。
■与以2、3.5、5和7L/min图案化之前相比，两种规格的阀门的MPG更高，23年的EOA更大，但在29A中更小，RF与EOA相反。在5升/分钟时，在45bpm下蚀刻后,两种规格中的RF都较低。然而，在70bpm时，23A的射频下降，在29A增加。
■小叶表面的平行凹槽图案影响瓣膜假体的血液动力学性能。
