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Abstract：
OBJECTIVE: To explore the patients\' satisfaction and health-related quality of life (HRQOL) of patients who received reconstruction after breast cancer surgery using the BREAST-Q questionnaire and further investigate the influencing risk factors.
METHODS: This cross-sectional study enrolled patients who underwent first-ever breast reconstruction after unilateral or bilateral mastectomy at the Breast Surgery Department of First Affiliated Hospital of Zhengzhou University or People\'s Hospital of Zhengzhou between January 2016 and December 2021. Multivariable linear regression analysis was used to analyze the risk factors.
RESULTS: A total of 202 participants were included. Age of >45 years (vs.≤35 years, β = - 3.74, P < 0.001) was an independent risk factor influencing the satisfaction degree score. Age between 36 and 45 years (vs. ≤35 years, β = - 0.26, P < 0.001), age of >45 years (vs. ≤35 years, β = - 0.45, P < 0.001), nipple-preserving mastectomy (NSM)/ skin-preserving mastectomy (SSM) + sentinel lymph node dissection + prosthesis implantation + contralateral breast augmentation (vs. NSM/SSM + sentinel lymph node dissection + prosthesis implantation, β = - 0.16, P=0.012), and the use of small intestinal submucosa (SIS) matrix (β = 0.13, P = 0.044) were independent risk factors influencing the HRQOL scores.
CONCLUSIONS: Age, the surgical procedure, and the use of matrix were associated with the satisfaction degree and HRQOL after breast reconstruction in patients receiving mastectomy.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
METHODS: This cross-sectional study enrolled patients who underwent first-ever breast reconstruction after unilateral or bilateral mastectomy at the Breast Surgery Department of First Affiliated Hospital of Zhengzhou University or People\'s Hospital of Zhengzhou between January 2016 and December 2021. Multivariable linear regression analysis was used to analyze the risk factors.
RESULTS: A total of 202 participants were included. Age of >45 years (vs.≤35 years, β = - 3.74, P < 0.001) was an independent risk factor influencing the satisfaction degree score. Age between 36 and 45 years (vs. ≤35 years, β = - 0.26, P < 0.001), age of >45 years (vs. ≤35 years, β = - 0.45, P < 0.001), nipple-preserving mastectomy (NSM)/ skin-preserving mastectomy (SSM) + sentinel lymph node dissection + prosthesis implantation + contralateral breast augmentation (vs. NSM/SSM + sentinel lymph node dissection + prosthesis implantation, β = - 0.16, P=0.012), and the use of small intestinal submucosa (SIS) matrix (β = 0.13, P = 0.044) were independent risk factors influencing the HRQOL scores.
CONCLUSIONS: Age, the surgical procedure, and the use of matrix were associated with the satisfaction degree and HRQOL after breast reconstruction in patients receiving mastectomy.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
摘要：
目的：采用BREAST-Q问卷对乳腺癌术后重建患者的满意度及健康相关生活质量（HRQOL）进行调查，并进一步探讨其影响因素。
方法：本横断面研究纳入2016年1月至2021年12月在郑州大学第一附属医院乳腺外科或郑州人民医院行单侧或双侧乳房切除术后首次乳房再造的患者。采用多元线性回归分析危险因素。
结果：共纳入202名参与者。年龄>45岁（vs.≤35年，β=-3.74,P<0.001)是影响满意度评分的独立危险因素。年龄在36至45岁之间（vs.≤35年，β=-0.26，P<0.001），年龄>45岁(vs.≤35年，β=-0.45，P<0.001），保留乳头乳房切除术(NSM)/保留皮肤乳房切除术(SSM)+前哨淋巴结清扫+假体植入+对侧隆胸(vs.NSM/SSM+前哨淋巴结清扫+假体植入,β=-0.16,P=0.012),使用小肠黏膜下层(SIS)基质(β=0.13,P=0.044)是影响HRQOL评分的独立危险因素。
结论：年龄，外科手术,矩阵的使用与乳房切除术后患者的满意度和HRQOL相关。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
方法：本横断面研究纳入2016年1月至2021年12月在郑州大学第一附属医院乳腺外科或郑州人民医院行单侧或双侧乳房切除术后首次乳房再造的患者。采用多元线性回归分析危险因素。
结果：共纳入202名参与者。年龄>45岁（vs.≤35年，β=-3.74,P<0.001)是影响满意度评分的独立危险因素。年龄在36至45岁之间（vs.≤35年，β=-0.26，P<0.001），年龄>45岁(vs.≤35年，β=-0.45，P<0.001），保留乳头乳房切除术(NSM)/保留皮肤乳房切除术(SSM)+前哨淋巴结清扫+假体植入+对侧隆胸(vs.NSM/SSM+前哨淋巴结清扫+假体植入,β=-0.16,P=0.012),使用小肠黏膜下层(SIS)基质(β=0.13,P=0.044)是影响HRQOL评分的独立危险因素。
结论：年龄，外科手术,矩阵的使用与乳房切除术后患者的满意度和HRQOL相关。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
