PDF(Pubmed)
Abstract：
OBJECTIVE: The purpose of this study was to investigate the correlation between triglyceride-glucose (TyG) index and cervical vascular function parameters in the general population without cerebrovascular disease.
METHODS: This was a cross-sectional study that recruited a total of 1996 participants without cerebrovascular disease. TyG index was calculated based on fasting triglycerides and glucose. All patients were divided into two groups based on the median TyG index: the high TyG group and the low TyG group. The differences in basic clinical characteristics and neck vascular function parameters between the two groups of participants were compared, and then the correlation between TyG index and neck vascular function parameters was investigated.
RESULTS: Participants with a high TyG index had lower systolic, diastolic, and mean flow velocities in the basilar, vertebral, and internal carotid arteries compared with those with a low TyG index. Participants with a high TyG index had higher pulsatility index in the left vertebral artery and right internal carotid artery, but this difference was not observed in the basilar artery. In addition, TyG index was significantly negatively correlated with systolic, diastolic, and mean flow velocities in the basilar, vertebral, and internal carotid arteries, and the correlation remained after adjusting for confounding factors.
CONCLUSIONS: In the general population, there was a well-defined correlation between TyG index and cervical vascular function parameters, and increased TyG index was independently associated with reduced cervical vascular blood flow velocity.
METHODS: This was a cross-sectional study that recruited a total of 1996 participants without cerebrovascular disease. TyG index was calculated based on fasting triglycerides and glucose. All patients were divided into two groups based on the median TyG index: the high TyG group and the low TyG group. The differences in basic clinical characteristics and neck vascular function parameters between the two groups of participants were compared, and then the correlation between TyG index and neck vascular function parameters was investigated.
RESULTS: Participants with a high TyG index had lower systolic, diastolic, and mean flow velocities in the basilar, vertebral, and internal carotid arteries compared with those with a low TyG index. Participants with a high TyG index had higher pulsatility index in the left vertebral artery and right internal carotid artery, but this difference was not observed in the basilar artery. In addition, TyG index was significantly negatively correlated with systolic, diastolic, and mean flow velocities in the basilar, vertebral, and internal carotid arteries, and the correlation remained after adjusting for confounding factors.
CONCLUSIONS: In the general population, there was a well-defined correlation between TyG index and cervical vascular function parameters, and increased TyG index was independently associated with reduced cervical vascular blood flow velocity.
摘要：
目的：本研究的目的是探讨无脑血管疾病的普通人群中甘油三酸酯-葡萄糖（TyG）指数与宫颈血管功能参数之间的相关性。
方法：这是一项横断面研究，共招募了1996名没有脑血管疾病的参与者。基于空腹甘油三酯和葡萄糖计算TyG指数。根据中位数TyG指数将所有患者分为两组：高TyG组和低TyG组。比较两组患者的基本临床特征和颈部血管功能参数的差异,然后研究了TyG指数与颈部血管功能参数之间的相关性。
结果：TyG指数高的参与者收缩压较低，舒张压,基底的平均流速，椎骨,与低TyG指数的颈内动脉相比。TyG指数高的参与者在左椎动脉和右颈内动脉的搏动指数较高，但是在基底动脉中没有观察到这种差异。此外,TyG指数与收缩压呈显著负相关,舒张压,基底的平均流速，椎骨,和颈内动脉，在调整混杂因素后，相关性仍然存在。
结论：在一般人群中，TyG指数与宫颈血管功能参数之间存在明确的相关性，TyG指数升高与颈部血管血流速度降低独立相关。
方法：这是一项横断面研究，共招募了1996名没有脑血管疾病的参与者。基于空腹甘油三酯和葡萄糖计算TyG指数。根据中位数TyG指数将所有患者分为两组：高TyG组和低TyG组。比较两组患者的基本临床特征和颈部血管功能参数的差异,然后研究了TyG指数与颈部血管功能参数之间的相关性。
结果：TyG指数高的参与者收缩压较低，舒张压,基底的平均流速，椎骨,与低TyG指数的颈内动脉相比。TyG指数高的参与者在左椎动脉和右颈内动脉的搏动指数较高，但是在基底动脉中没有观察到这种差异。此外,TyG指数与收缩压呈显著负相关,舒张压,基底的平均流速，椎骨,和颈内动脉，在调整混杂因素后，相关性仍然存在。
结论：在一般人群中，TyG指数与宫颈血管功能参数之间存在明确的相关性，TyG指数升高与颈部血管血流速度降低独立相关。
