PDF(Pubmed)
Abstract：
UNASSIGNED: Healthcare-associated infections are a major concern for healthcare systems around the world. Microorganisms developing resistance to potent antibiotics are an urgent threat to public health.
UNASSIGNED: The present study is a retrospective, single-center study performed at the Mina Minovici National Institute of Legal Medicine, Bucharest, Romania, over a period of ten years (2011-2020). Autopsies for deaths occurring in the hospital setting for which postmortem bacteriological examination was solicited were screened and the recovered data consisted of demographics, hospital stay duration, autopsy data, and postmortem microbiology.
UNASSIGNED: In the 516 autopsies recovered we found that carbapenemase-producing Enterobacteriaceae (CPE) isolates from postmortem bacteriology results increased in 2019. Positive postmortem microbiology results were associated with histological infection in over 80% of cases. Positive results for healthcare-related pathogens were associated with prolonged hospital stay. In our data vancomycin-resistant enterococci were isolated from 2015.
UNASSIGNED: Postmortem bacteriology results from medico-legal autopsies mirror antimicrobial resistance trends from hospital settings with several limitations due to the scarcity of solicitations.
UNASSIGNED: The present study is a retrospective, single-center study performed at the Mina Minovici National Institute of Legal Medicine, Bucharest, Romania, over a period of ten years (2011-2020). Autopsies for deaths occurring in the hospital setting for which postmortem bacteriological examination was solicited were screened and the recovered data consisted of demographics, hospital stay duration, autopsy data, and postmortem microbiology.
UNASSIGNED: In the 516 autopsies recovered we found that carbapenemase-producing Enterobacteriaceae (CPE) isolates from postmortem bacteriology results increased in 2019. Positive postmortem microbiology results were associated with histological infection in over 80% of cases. Positive results for healthcare-related pathogens were associated with prolonged hospital stay. In our data vancomycin-resistant enterococci were isolated from 2015.
UNASSIGNED: Postmortem bacteriology results from medico-legal autopsies mirror antimicrobial resistance trends from hospital settings with several limitations due to the scarcity of solicitations.
摘要：
医疗保健相关感染是全世界医疗保健系统的主要关注点。对强效抗生素产生耐药性的微生物是对公众健康的紧迫威胁。
■本研究是一项回顾性研究，在MinaMinovici国家法律医学研究所进行的单中心研究，布加勒斯特,罗马尼亚,为期十年（2011-2020年）。对医院环境中发生的死亡进行尸体解剖，并进行了尸检，其中要求进行尸检，并且恢复的数据包括人口统计学，住院时间,尸检数据,和死后微生物学。
■在516例尸检中，我们发现，来自死后细菌学结果的产碳青霉烯酶肠杆菌科（CPE）分离株在2019年增加。在超过80％的病例中，死后微生物学结果阳性与组织学感染有关。医疗保健相关病原体的阳性结果与住院时间延长有关。在我们的数据中，万古霉素耐药肠球菌是从2015年分离的。
■法医学尸检的死后细菌学结果反映了医院环境中的抗菌素耐药性趋势，但由于缺乏邀请，存在一些局限性。
■本研究是一项回顾性研究，在MinaMinovici国家法律医学研究所进行的单中心研究，布加勒斯特,罗马尼亚,为期十年（2011-2020年）。对医院环境中发生的死亡进行尸体解剖，并进行了尸检，其中要求进行尸检，并且恢复的数据包括人口统计学，住院时间,尸检数据,和死后微生物学。
■在516例尸检中，我们发现，来自死后细菌学结果的产碳青霉烯酶肠杆菌科（CPE）分离株在2019年增加。在超过80％的病例中，死后微生物学结果阳性与组织学感染有关。医疗保健相关病原体的阳性结果与住院时间延长有关。在我们的数据中，万古霉素耐药肠球菌是从2015年分离的。
■法医学尸检的死后细菌学结果反映了医院环境中的抗菌素耐药性趋势，但由于缺乏邀请，存在一些局限性。
