Abstract：
Parkinson\'s disease (PD) is a common and disabling neurodegenerative disorder with a prevalence set to double by 2030. People with PD present both motor symptoms (such as tremor, rigidity, slowness of movements, and postural instability) and non-motor symptoms (such as dementia, psychiatric symptoms, and sleep disturbances). The treatment of PD is challenging and is highly individualized. The Taiwan Movement Disorder Society (TMDS) has published its treatment recommendations for PD in 2017. Since then, because the advent of medical and device-aided therapy has developed rapidly, the TMDS has recognized the need to disseminate the updated knowledge about the management of PD. The TMDS acknowledges the importance of evidence-based medicine (EBM) in clinical practice. Therefore, we strive to align our treatment recommendations with EBM principles. Nevertheless, it still needs to be emphasized that therapeutic recommendations should always be tailored to the individual patient, based not only on an accurate understanding of the efficacy and side effect profile of available treatments (the primary focus of guidelines), but also the physician\'s judgment, patient\'s preference, and the regulations of national health insurance. To ensure that the updated Taiwan treatment suggestions are appropriate and feasible, the treatment guideline subcommittee of TMDS referred to the guidelines from the International Movement Disorder Society and other treatment suggestions from United States and Europe concerning the level of evidence, recommendation levels, clinical efficacy, and potential adverse reactions of therapeutics for the treatment of motor and non-motor symptoms of PD. By incorporating the latest research, international guidelines, and treatment suggestions, the TMDS aims to provide comprehensive and up-to-date recommendations for the management of PD in Taiwan. These recommendations serve as a valuable resource for healthcare professionals to enhance their understanding of PD treatment options and optimize patient care. Key Words: Parkinson\'s disease; treatment; guidelines; evidence-based medicine.
摘要：
帕金森病（PD）是一种常见且致残的神经退行性疾病，到2030年患病率将增加一倍。患有PD的人同时表现出两种运动症状(如震颤，刚性,运动缓慢，和姿势不稳定)和非运动症状(如痴呆症，精神症状,和睡眠障碍)。PD的治疗是具有挑战性的并且是高度个体化的。台湾运动障碍协会（TMDS）于2017年发布了其对PD的治疗建议。从那以后,因为医疗和设备辅助治疗的出现发展迅速，TMDS认识到有必要传播有关PD管理的最新知识。TMDS承认循证医学（EBM）在临床实践中的重要性。因此,我们努力使我们的治疗建议与EBM原则保持一致。然而，仍然需要强调的是，治疗建议应始终针对个体患者量身定制，不仅基于对现有治疗方法的疗效和副作用的准确理解（指南的主要重点），还有医生的判断，患者的偏好，以及国民健康保险的规定。确保更新后的台湾治疗建议适当可行,TMDS的治疗指南小组委员会参考了国际运动障碍协会的指南以及美国和欧洲关于证据水平的其他治疗建议，推荐级别,临床疗效,以及用于治疗PD的运动和非运动症状的治疗剂的潜在不良反应。通过结合最新的研究，国际准则,和治疗建议，TMDS旨在为台湾PD的管理提供全面和最新的建议。这些建议为医疗保健专业人员提供了宝贵的资源，以增强他们对PD治疗方案的理解并优化患者护理。关键词：帕金森病；治疗；指南；循证医学.
