Abstract:
Primary hemostatic disorders such as thrombocytopenia and thrombocytopathia are commonly encountered in small animal practice. The key stages of primary hemostasis include platelet adhesion, activation, and aggregation. Understanding the interaction between tissues, platelets, and signaling molecules not only helps clinicians comprehend clot formation but also better recognize thrombocytopathias. Although congenital thrombocytopathia is rare, commercially available platelet function tests allow veterinarians to narrow differentials in many clinical settings. Thrombocytopenia can be easily diagnosed in any clinical setting. In this paper, we review the current understanding of primary hemostasis in veterinary medicine, including the clinical presentation and available diagnostics to identify platelet abnormalities.
摘要:
原发性止血疾病如血小板减少症和血小板病变在小动物实践中经常遇到。初级止血的关键阶段包括血小板粘附,激活和聚合。了解组织之间的相互作用,血小板,和信号分子不仅有助于临床医生理解血凝块的形成,还可以更好地识别血小板减少。虽然先天性血小板病变是罕见的,市售的血小板功能测试允许兽医在许多临床环境中缩小差异。血小板减少症可以在任何临床环境中容易地诊断。在本文中,我们回顾了当前对兽医学中初级止血的理解,包括临床表现和可用的诊断,以确定血小板异常。