PDF(Pubmed)
Abstract：
Multiple trichoepithelioma syndrome is a rare entity, and little is known about its epidemiological features. Patients usually present with multiple nonsuspicious skin lesions. Surgical excision is the mainstay of treatment, and diagnosis is usually made after the first pathology report. Once the diagnosis is established, patients are kept under clinical surveillance, and surgery is performed again if tumor burden and/or size justifies it. The authors present a male patient who presented to our outpatient clinic for the first time in 36 years without any relevant medical history, medication, or allergies. The patient had complaints of multiple skin lesions spreading across the head and neck regions. Surgical excision of the affected area and resurfacing using local advancement flaps were performed. Pathology reports were always consistent with trichoepitheliomas. No pathology of spiradenoma or cylindroma was ever reported. Usually, tumors are small enough for simple excision and primary closure. However, in the presented case, the size of the tumor and the involvement of central facial aesthetic units demanded a more complex approach.
摘要：
多发性毛发上皮瘤综合征是一种罕见的实体，对其流行病学特征知之甚少。患者通常表现为多个非可疑皮肤病变。手术切除是治疗的主要手段,诊断通常在第一次病理报告后进行。一旦诊断确定，病人接受临床监测,如果肿瘤负荷和/或大小证明是合理的，则再次进行手术。作者介绍了一名男性患者，该患者36年来首次到我们的门诊就诊，没有任何相关病史，药物,或过敏。患者抱怨多个皮肤病变遍布头部和颈部。进行了受影响区域的手术切除和使用局部前移皮瓣进行表面修复。病理报告始终与毛发上皮瘤一致。从未报告过螺旋腺瘤或圆柱瘤的病理。通常,肿瘤足够小，可以进行简单的切除和原发性闭合。然而,在提出的情况下，肿瘤的大小和中央面部美学单元的参与需要更复杂的方法。
