Abstract：
BACKGROUND: Hair diseases may present with hair loss, hirsutism, hair melanin abnormalities and other manifestations. Hair follicles are known as mini-organs that undergo periodic remodeling, and their constant regeneration in vivo reflects interesting anti-aging functions. Telomerase prevents cellular senescence by maintaining telomere length, but its excessive proliferation in cancer cells may also induce cancer. However, the effects of telomerase in hair growth have rarely been reported.
METHODS: In this study, we reviewed the role of telomerase in hair growth and the effects of hair disorders through literature search and analysis.
RESULTS: There is growing evidence that telomerase plays an important role in maintaining hair follicle function and proliferation. Changes in telomerase levels in hair follicles have also been found in a variety of hair disorders.
CONCLUSIONS: Telomerase plays a positive role in hair growth and is expected to become a new target for the treatment of alopecia or other hair diseases in the future.
METHODS: In this study, we reviewed the role of telomerase in hair growth and the effects of hair disorders through literature search and analysis.
RESULTS: There is growing evidence that telomerase plays an important role in maintaining hair follicle function and proliferation. Changes in telomerase levels in hair follicles have also been found in a variety of hair disorders.
CONCLUSIONS: Telomerase plays a positive role in hair growth and is expected to become a new target for the treatment of alopecia or other hair diseases in the future.
摘要：
背景：头发疾病可能伴随脱发，多毛症,头发黑色素异常等表现。毛囊被称为经历周期性重塑的微型器官，它们在体内的不断再生反映了有趣的抗衰老功能。端粒酶通过维持端粒长度来防止细胞衰老，但它在癌细胞中的过度增殖也可能诱发癌症。然而,端粒酶对头发生长的影响鲜有报道。
方法：在本研究中，通过文献检索和分析,对端粒酶在毛发生长中的作用及毛发疾病的影响进行综述。
结果：越来越多的证据表明，端粒酶在维持毛囊功能和增殖中起着重要作用。在各种毛发疾病中也发现了毛囊中端粒酶水平的变化。
结论：端粒酶在毛发生长中起积极作用，有望成为未来治疗脱发或其他毛发疾病的新靶点。
方法：在本研究中，通过文献检索和分析,对端粒酶在毛发生长中的作用及毛发疾病的影响进行综述。
结果：越来越多的证据表明，端粒酶在维持毛囊功能和增殖中起着重要作用。在各种毛发疾病中也发现了毛囊中端粒酶水平的变化。
结论：端粒酶在毛发生长中起积极作用，有望成为未来治疗脱发或其他毛发疾病的新靶点。
