Abstract：
BACKGROUND: Infancy is a complex period of human life, in which environmental experiences have a fundamental role for neurodevelopment. Although conditions of social and sensory deprivation are uncommon in high income countries, the Covid-19 pandemic abruptly modified this condition, by depriving people of their social stimuli of daily life.
OBJECTIVE: To understand the impact of this deprivation on infants\' behaviour, we investigated the short-term effects of isolation and use of individual protective systems by mothers during the first two weeks of life.
METHODS: The study included 11 mother-infant dyads with mothers tested positive to SARS-CoV-2 at the time of delivery (Covid group) and 11 dyads with a SARS-CoV-2 negative mother as controls. Neurobehavioral, visual, and sensory processing assessments were performed from birth to 3 months of age.
RESULTS: Findings showed the effect of deprivation on some neurobehavioral abilities of infants in the Covid group; in addition, differences in sensory maturation trends were observed, although they tended to gradually decrease until disappearance at 3 months of age.
CONCLUSIONS: These findings suggest the significant effects of early sensory and social deprivation during the first two weeks of life, but also provide several insights on the ability of the brain to restore its aptitudes by deleting or reducing the effects of early deprivation before the critical periods\' closure.
OBJECTIVE: To understand the impact of this deprivation on infants\' behaviour, we investigated the short-term effects of isolation and use of individual protective systems by mothers during the first two weeks of life.
METHODS: The study included 11 mother-infant dyads with mothers tested positive to SARS-CoV-2 at the time of delivery (Covid group) and 11 dyads with a SARS-CoV-2 negative mother as controls. Neurobehavioral, visual, and sensory processing assessments were performed from birth to 3 months of age.
RESULTS: Findings showed the effect of deprivation on some neurobehavioral abilities of infants in the Covid group; in addition, differences in sensory maturation trends were observed, although they tended to gradually decrease until disappearance at 3 months of age.
CONCLUSIONS: These findings suggest the significant effects of early sensory and social deprivation during the first two weeks of life, but also provide several insights on the ability of the brain to restore its aptitudes by deleting or reducing the effects of early deprivation before the critical periods\' closure.
摘要：
背景：婴儿期是人类生活的复杂时期，其中环境经验对神经发育具有基本作用。尽管社会和感官剥夺的条件在高收入国家并不常见，Covid-19大流行突然改变了这种情况，剥夺人们日常生活的社会刺激。
目的：为了了解这种剥夺对婴儿行为的影响，我们调查了母亲在出生后前两周隔离和使用个体保护系统的短期影响.
方法：该研究包括11个母婴二分体，其中母亲在分娩时对SARS-CoV-2检测呈阳性（Covid组），11个二分体以SARS-CoV-2阴性母亲作为对照。神经行为学,视觉，从出生到3月龄进行感官处理评估.
结果：研究结果表明，在Covid组中，剥夺对婴儿的某些神经行为能力的影响；此外，观察到感官成熟趋势的差异，尽管它们趋于逐渐减少，直到3个月大时消失。
结论：这些发现表明，在生命的前两周，早期感觉和社交剥夺会产生重大影响，但也提供了一些关于大脑恢复能力的见解，通过在关键时期关闭之前删除或减少早期剥夺的影响。
目的：为了了解这种剥夺对婴儿行为的影响，我们调查了母亲在出生后前两周隔离和使用个体保护系统的短期影响.
方法：该研究包括11个母婴二分体，其中母亲在分娩时对SARS-CoV-2检测呈阳性（Covid组），11个二分体以SARS-CoV-2阴性母亲作为对照。神经行为学,视觉，从出生到3月龄进行感官处理评估.
结果：研究结果表明，在Covid组中，剥夺对婴儿的某些神经行为能力的影响；此外，观察到感官成熟趋势的差异，尽管它们趋于逐渐减少，直到3个月大时消失。
结论：这些发现表明，在生命的前两周，早期感觉和社交剥夺会产生重大影响，但也提供了一些关于大脑恢复能力的见解，通过在关键时期关闭之前删除或减少早期剥夺的影响。
