Abstract:
The existing data have shown inconsistency about the association between red cell distribution width (RDW) and hypertension. Thus, the aim of the present study was to investigate the association between RDW and newly diagnosed hypertension among adults in Sudan. This was a case-control study conducted in Northern Sudan from July to September 2022. The cases were patients with newly diagnosed hypertension (n = 78), and the controls were healthy participants (n = 78). A questionnaire was used to collect the participants\' sociodemographic, and clinical data. RDW was measured using an automated hematology analyzer. A logistic regression analysis was performed. The univariate analysis revealed no association between sex, educational level, occupational level, RDW, and newly diagnosed hypertension. In the multivariate analysis, increasing age (adjusted odds ratio [AOR], 1.05; 95% confidence interval [CI], 1.02‒1.08) and body mass index (AOR, 1.12; 95% CI, 1.05‒1.19) were associated with newly diagnosed hypertension. No association was found between RDW and newly diagnosed hypertension. No correlation was found between RDW and systolic (r = 0.045, P = 0.577) or diastolic blood pressure (r = 0.023, P = 0.772). In conclusion, no association in RDW was found between the patients with newly diagnosed hypertension and the healthy controls.
摘要:
现有数据显示红细胞分布宽度(RDW)与高血压之间的关联不一致。因此,本研究的目的是调查苏丹成年人中RDW与新诊断的高血压之间的关系.这是2022年7月至9月在苏丹北部进行的病例对照研究。这些病例为新诊断的高血压患者(n=78),对照组为健康参与者(n=78)。问卷被用来收集参与者的社会人口统计,和临床数据。使用自动血液学分析仪测量RDW。进行逻辑回归分析。单因素分析显示性别之间没有关联,教育水平,职业水平,RDW,和新诊断的高血压。在多变量分析中,年龄增加(调整后的赔率比[AOR],1.05;95%置信区间[CI],1.02-1.08)和体重指数(AOR,1.12;95%CI,1.05±1.19)与新诊断的高血压相关。RDW与新诊断的高血压之间未发现关联。RDW与收缩压(r=0.045,P=0.577)和舒张压(r=0.023,P=0.772)无相关性。总之,在新诊断的高血压患者和健康对照组之间未发现RDW相关.