PDF(Pubmed)
Abstract：
Head and neck cancers represent a significant source of morbidity and mortality across the world. The individual genetic makeup of each tumor can help to determine the course of treatment and can help clinicians predict prognosis. Non-invasive tools to determine the genetic status of these tumors, particularly p16 (human papillomavirus (HPV)) status could prove extremely valuable to treating clinicians and surgeons. The field of radiomics is a burgeoning area of radiology practice that aims to provide quantitative biomarkers that can be derived from radiological images and could prove useful in determining p16 status non-invasively. In this review, we summarize the current evidence for the use of radiomics to determine the HPV status of head and neck tumors. .
摘要：
头颈癌是全世界发病率和死亡率的重要来源。每个肿瘤的个体遗传组成可以帮助确定治疗过程，并可以帮助临床医生预测预后。非侵入性工具来确定这些肿瘤的遗传状态，尤其是p16(人乳头瘤病毒(HPV))状态可能被证明对临床医生和外科医生极具价值.放射组学领域是放射学实践的新兴领域，旨在提供可以从放射学图像中得出的定量生物标志物，并且可以证明对无创地确定p16状态有用。在这次审查中,我们总结了目前使用影像组学确定头颈部肿瘤HPV状态的证据..
