PDF(Pubmed)
Abstract：
UNASSIGNED: In 2014, Ozaki et al. introduced the neo-cuspidation (Ozaki procedure), a new valve from the pericardium, to reduce or even prevent the risk of chronic autoimmune inflammation and subsequent rejection or valve degeneration. Thus, the authors aimed to assess the safety and efficacy of the Ozaki technique in treating aortic valve diseases.
UNASSIGNED: A comprehensive search was performed via PubMed, the Cochrane Library, Scopus, and the Web of Science up to 20 February 2022. Random-effects meta-analysis models were employed to estimate the pooled mean and SD or event to the total of the Ozaki procedure. Relevant records were retrieved and analyzed by OpenMeta analyst software.
UNASSIGNED: A total of 2863 patients from 21 studies were finally included in our analysis. Ac. Ozaki technique showed statistical significance in terms of mean cardiopulmonary bypass time of 148 mins (95% CI 144-152.2, P<0.001), mean aortic cross-clamp time of 112.46 mins (95% CI 105.116, 119.823, P<0.001), reoperation with a low risk of 0.011 (95% CI 0.005, 0.016, P=0.047), conversion to aortic valve replacement with a low risk of 0.004 (95% CI -0.001, 0.008, P=0.392), finally ICU stay (days) and hospital length of stay (days) with a mean of 2.061 days (95% CI 1.535, 2.587, P<0.001) and 8.159 days (95% CI 7.183-9.855, P<0.001), respectively.
UNASSIGNED: The Ozaki procedure provides a safe surgical technique with low mean cardiopulmonary bypass time and aortic cross-clamp time; moreover, a mean of 2-day-postoperative hospital stay was observed with the Ozaki procedure with a low risk of conversion to aortic valve replacement, reoperation, ICU and hospital stay, and death.
UNASSIGNED: A comprehensive search was performed via PubMed, the Cochrane Library, Scopus, and the Web of Science up to 20 February 2022. Random-effects meta-analysis models were employed to estimate the pooled mean and SD or event to the total of the Ozaki procedure. Relevant records were retrieved and analyzed by OpenMeta analyst software.
UNASSIGNED: A total of 2863 patients from 21 studies were finally included in our analysis. Ac. Ozaki technique showed statistical significance in terms of mean cardiopulmonary bypass time of 148 mins (95% CI 144-152.2, P<0.001), mean aortic cross-clamp time of 112.46 mins (95% CI 105.116, 119.823, P<0.001), reoperation with a low risk of 0.011 (95% CI 0.005, 0.016, P=0.047), conversion to aortic valve replacement with a low risk of 0.004 (95% CI -0.001, 0.008, P=0.392), finally ICU stay (days) and hospital length of stay (days) with a mean of 2.061 days (95% CI 1.535, 2.587, P<0.001) and 8.159 days (95% CI 7.183-9.855, P<0.001), respectively.
UNASSIGNED: The Ozaki procedure provides a safe surgical technique with low mean cardiopulmonary bypass time and aortic cross-clamp time; moreover, a mean of 2-day-postoperative hospital stay was observed with the Ozaki procedure with a low risk of conversion to aortic valve replacement, reoperation, ICU and hospital stay, and death.
摘要：
■2014年，Ozaki等人。引入了新讨论(Ozaki程序)，心包的新瓣膜,降低甚至预防慢性自身免疫性炎症和随后的排斥反应或瓣膜变性的风险。因此，作者旨在评估Ozaki技术治疗主动脉瓣疾病的安全性和有效性.
■通过PubMed进行了全面搜索，Cochrane图书馆,Scopus,和WebofScience至2022年2月20日。使用随机效应荟萃分析模型来估计Ozaki程序的合并平均值和SD或事件。相关记录通过OpenMeta分析软件进行检索和分析。
■21项研究中的2863名患者最终纳入我们的分析。AC。Ozaki技术在148分钟的平均体外循环时间方面显示出统计学意义（95％CI144-152.2，P<0.001），平均主动脉阻断时间112.46分钟(95%CI105.116,119.823,P<0.001),再次手术的低风险为0.011（95％CI0.005，0.016，P=0.047），转换为主动脉瓣置换术的低风险为0.004（95％CI-0.001，0.008，P=0.392），最终ICU住院时间（天数）和住院时间（天数），平均为2.061天（95％CI1.535，2.587，P<0.001）和8.159天（95％CI7.183-9.855，P<0.001），分别。
■Ozaki手术提供了一种安全的手术技术，具有较低的平均体外循环时间和主动脉交叉钳夹时间；此外，观察到Ozaki手术后平均2天的住院时间，转换为主动脉瓣置换术的风险较低，再操作,ICU和住院时间，和死亡。
■通过PubMed进行了全面搜索，Cochrane图书馆,Scopus,和WebofScience至2022年2月20日。使用随机效应荟萃分析模型来估计Ozaki程序的合并平均值和SD或事件。相关记录通过OpenMeta分析软件进行检索和分析。
■21项研究中的2863名患者最终纳入我们的分析。AC。Ozaki技术在148分钟的平均体外循环时间方面显示出统计学意义（95％CI144-152.2，P<0.001），平均主动脉阻断时间112.46分钟(95%CI105.116,119.823,P<0.001),再次手术的低风险为0.011（95％CI0.005，0.016，P=0.047），转换为主动脉瓣置换术的低风险为0.004（95％CI-0.001，0.008，P=0.392），最终ICU住院时间（天数）和住院时间（天数），平均为2.061天（95％CI1.535，2.587，P<0.001）和8.159天（95％CI7.183-9.855，P<0.001），分别。
■Ozaki手术提供了一种安全的手术技术，具有较低的平均体外循环时间和主动脉交叉钳夹时间；此外，观察到Ozaki手术后平均2天的住院时间，转换为主动脉瓣置换术的风险较低，再操作,ICU和住院时间，和死亡。
