PDF(Pubmed)
Abstract：
UNASSIGNED: Granular cell tumors (GCTs) are uncommon soft tissue tumors, predominantly benign lesions. Approximately 50% occur in the tongue, with a peak incidence in the fifth and sixth decades of life. However, in this case, a rare presentation of GCTs on the cheek of a 16-year-old young female, including a review of the literature.
UNASSIGNED: The medical records and histopathological slides of the case were retrospectively reviewed. This work has been reported based on Surgical CAse REport (SCARE) criteria.
UNASSIGNED: A 16-year-old female presented with a non-painful exophytic and pigmented cheek lesion that is rapidly growing. A primary concern was expressed as cosmetic in nature, a biopsy of the mass was taken, and histopathological findings showed a malignant tumor, mostly consistent with GCTs. She was recommended to have a total excision of the mass. During follow-up, facial MRI findings indicate granulation tissue versus recurrent/residual tumor at the site of surgery, without any evidence of cancer metastasis or spread.
UNASSIGNED: GCT is a tumor of Schwann cells, which is mostly benign with a 2% risk of malignant transformation. The peak incidence of this tumor is around the age of 50, and it is uncommon in young individuals. Clinically, GCT presents as a single, asymptomatic dermal or subcutaneous, brown-red nodule or papule, which grows slowly with diameter ranging from 0.5 to 3 cm. The definitive treatment for both benign and malignant GCTs is sufficient local excision with safe margins.
UNASSIGNED: GCT is an extremely rare tumor, with a peak incidence of fifth and sixth decay of age, which usually appear in the tongue (50% of cases); however, in this case, we present a 16-year-old female with a cheek mass diagnosed as GCT. In short, we think that GCT should be considered as one of the differential diagnoses of solitary facial masses at young ages.
UNASSIGNED: The medical records and histopathological slides of the case were retrospectively reviewed. This work has been reported based on Surgical CAse REport (SCARE) criteria.
UNASSIGNED: A 16-year-old female presented with a non-painful exophytic and pigmented cheek lesion that is rapidly growing. A primary concern was expressed as cosmetic in nature, a biopsy of the mass was taken, and histopathological findings showed a malignant tumor, mostly consistent with GCTs. She was recommended to have a total excision of the mass. During follow-up, facial MRI findings indicate granulation tissue versus recurrent/residual tumor at the site of surgery, without any evidence of cancer metastasis or spread.
UNASSIGNED: GCT is a tumor of Schwann cells, which is mostly benign with a 2% risk of malignant transformation. The peak incidence of this tumor is around the age of 50, and it is uncommon in young individuals. Clinically, GCT presents as a single, asymptomatic dermal or subcutaneous, brown-red nodule or papule, which grows slowly with diameter ranging from 0.5 to 3 cm. The definitive treatment for both benign and malignant GCTs is sufficient local excision with safe margins.
UNASSIGNED: GCT is an extremely rare tumor, with a peak incidence of fifth and sixth decay of age, which usually appear in the tongue (50% of cases); however, in this case, we present a 16-year-old female with a cheek mass diagnosed as GCT. In short, we think that GCT should be considered as one of the differential diagnoses of solitary facial masses at young ages.
摘要：
■颗粒细胞瘤（GCT）是不常见的软组织肿瘤，以良性病变为主.大约50%发生在舌头上，在生命的第五和六十年中发病率最高。然而,在这种情况下,一名16岁年轻女性脸颊上罕见的GCT，包括文献综述。
■对病例的病历和组织病理学切片进行回顾性分析。这项工作已根据外科CAse报告（SCARE）标准进行了报道。
■一名16岁的女性表现为非疼痛的外生性和色素沉着的脸颊病变，并且正在迅速增长。人们主要关注的是化妆品性质，对肿块进行了活检，组织病理学发现显示为恶性肿瘤，大部分与GCT一致。建议她完全切除肿块。随访期间,面部MRI表现显示肉芽组织与手术部位复发/残留肿瘤相比，没有任何癌症转移或扩散的证据。
■GCT是一种雪旺氏细胞肿瘤，大部分是良性的，恶性转化的风险为2%。这种肿瘤的发病率高峰在50岁左右，在年轻人中并不常见。临床上,GCT作为一个单一的，无症状的真皮或皮下，棕红色结节或丘疹，其生长缓慢，直径范围从0.5到3厘米。良性和恶性GCT的最终治疗是足够的局部切除和安全的边缘。
■GCT是一种极其罕见的肿瘤,年龄第五和第六衰减的发生率最高，通常出现在舌头（50％的病例）;然而，在这种情况下,我们介绍了一名16岁女性，其脸颊肿块被诊断为GCT。总之,我们认为GCT应被视为年轻时孤立性面部肿块的鉴别诊断之一。
■对病例的病历和组织病理学切片进行回顾性分析。这项工作已根据外科CAse报告（SCARE）标准进行了报道。
■一名16岁的女性表现为非疼痛的外生性和色素沉着的脸颊病变，并且正在迅速增长。人们主要关注的是化妆品性质，对肿块进行了活检，组织病理学发现显示为恶性肿瘤，大部分与GCT一致。建议她完全切除肿块。随访期间,面部MRI表现显示肉芽组织与手术部位复发/残留肿瘤相比，没有任何癌症转移或扩散的证据。
■GCT是一种雪旺氏细胞肿瘤，大部分是良性的，恶性转化的风险为2%。这种肿瘤的发病率高峰在50岁左右，在年轻人中并不常见。临床上,GCT作为一个单一的，无症状的真皮或皮下，棕红色结节或丘疹，其生长缓慢，直径范围从0.5到3厘米。良性和恶性GCT的最终治疗是足够的局部切除和安全的边缘。
■GCT是一种极其罕见的肿瘤,年龄第五和第六衰减的发生率最高，通常出现在舌头（50％的病例）;然而，在这种情况下,我们介绍了一名16岁女性，其脸颊肿块被诊断为GCT。总之,我们认为GCT应被视为年轻时孤立性面部肿块的鉴别诊断之一。
