METHODS: Out of a continuous series of 54 patients who received an ABI between 2005 and 2019, 23 Neurofibromatosis Type 2 patients with complete documentation of 154 recordings were selected for offline analysis and for development and evaluation of a new EABR Classification Scheme comprising Class A: three vertex positive peaks, Class B:two peaks, Class C: a combination of one peak and a second melted double peak, Class D: one sole vertex positive peak and Class E: no peaks.
RESULTS: All 23 subjects showed EABR at final ABI position and experienced auditory sensations at first activation. The most frequent morphology consisted of two peaks, Classes B and C. Identified mean latencies were for P1 0.42 ms (±0.095), P2 1.42 ms (±0.244) and P3 2.41 ms (±0.329). Peak latencies correlated positively with tumor extensions (p < 0.005).
CONCLUSIONS: This study provides clear instructions on optimal EABR performance and evaluation.
CONCLUSIONS: The new EABR Classification Scheme relies on a fast \"online\" identification of vertex positive peaks at the estimated post-artifact phase. The variability in EABR morphology provides an individual snapshot of the actual structural and functional status of the brainstem.
方法:在2005年至2019年期间接受ABI的54例连续系列患者中,选择23例2型神经纤维瘤病患者进行离线分析,并开发和评估包含A类的新EABR分类方案:三个顶点阳性峰,乙级:两峰,C类:一个峰和第二个熔化的双峰的组合,D类:一个单一顶点正峰,E类:无峰。
结果:所有23名受试者在最终ABI位置均显示EABR,并在首次激活时经历听觉感觉。最常见的形态由两个峰组成,B类和C类。确定的平均延迟为P10.42ms(±0.095),P21.42ms(±0.244)和P32.41ms(±0.329)。峰值潜伏期与肿瘤扩展呈正相关(p<0.005)。
结论:本研究提供了有关最佳EABR性能和评估的明确说明。
结论:新的EABR分类方案依赖于在估计的后伪影阶段快速“在线”识别顶点正峰。EABR形态的可变性提供了脑干实际结构和功能状态的个体快照。