PDF(Pubmed)
Abstract：
Diet quality is a significant determinant in the etiology of breast cancer (BrCa), but further studies are required to explore this relationship. Therefore, we tried to assess if diet quality, assessed using the Diet Quality Index-International (DQI-I), was related to BrCa among the Iranian population.
In the present case-control research, 134 women with a recent diagnosis of BrCa and 267 without BrCa were selected as case and control groups. Individual food intake data from a food frequency questionnaire was used to compute DQI-I. Also, the multivariable logistic regression models were utilized to evaluate the association between DQI-I and BrCa odds .
We found a significant association between the last tertile of DQI-I and BrCa odds in the fully adjusted model (odds ratio (OR) = 0.30; 95% confidence interval (CI): 0.15-0.56). The subgroup analysis based on menopausal status also showed a significant decrease in BrCa odds in pre-and post-menopausal women (pre-menopausal: OR = 0.27; 95% CI: 0.10-0.70 - post-menopausal status: OR = 0.35; 95% CI: 0.13-0.92).
Our findings indicated that a higher DQI-I score was related to a lower chance of BrCa. According to our research, a healthy diet pattern is crucial for BrCa prevention.
In the present case-control research, 134 women with a recent diagnosis of BrCa and 267 without BrCa were selected as case and control groups. Individual food intake data from a food frequency questionnaire was used to compute DQI-I. Also, the multivariable logistic regression models were utilized to evaluate the association between DQI-I and BrCa odds .
We found a significant association between the last tertile of DQI-I and BrCa odds in the fully adjusted model (odds ratio (OR) = 0.30; 95% confidence interval (CI): 0.15-0.56). The subgroup analysis based on menopausal status also showed a significant decrease in BrCa odds in pre-and post-menopausal women (pre-menopausal: OR = 0.27; 95% CI: 0.10-0.70 - post-menopausal status: OR = 0.35; 95% CI: 0.13-0.92).
Our findings indicated that a higher DQI-I score was related to a lower chance of BrCa. According to our research, a healthy diet pattern is crucial for BrCa prevention.
摘要：
背景：饮食质量是乳腺癌（BrCa）病因的重要决定因素，但是需要进一步的研究来探索这种关系。因此,我们试图评估饮食质量，使用国际饮食质量指数(DQI-I)进行评估，与伊朗人口中的BrCa有关。
方法：在本病例对照研究中，选择最近诊断为BrCa的134名妇女和无BrCa的267名妇女作为病例组和对照组。来自食物频率问卷的个体食物摄入量数据用于计算DQI-I。此外，利用多变量逻辑回归模型评估DQI-I与BrCa比值之间的关联.
结果：我们发现，在完全调整模型中，DQI-I的最后一个三分位数与BrCa赔率之间存在显著关联（优势比（OR）=0.30；95%置信区间（CI）：0.15-0.56）。基于绝经状态的亚组分析还显示，绝经前和绝经后妇女的BrCa几率显着降低（绝经前：OR=0.27；95％CI：0.10-0.70-绝经后状态：OR=0.35；95％CI：0.13-0.92）。
结论：我们的研究结果表明，较高的DQI-I评分与较低的BrCa发生率相关。根据我们的研究,健康的饮食模式对于预防BrCa至关重要。
方法：在本病例对照研究中，选择最近诊断为BrCa的134名妇女和无BrCa的267名妇女作为病例组和对照组。来自食物频率问卷的个体食物摄入量数据用于计算DQI-I。此外，利用多变量逻辑回归模型评估DQI-I与BrCa比值之间的关联.
结果：我们发现，在完全调整模型中，DQI-I的最后一个三分位数与BrCa赔率之间存在显著关联（优势比（OR）=0.30；95%置信区间（CI）：0.15-0.56）。基于绝经状态的亚组分析还显示，绝经前和绝经后妇女的BrCa几率显着降低（绝经前：OR=0.27；95％CI：0.10-0.70-绝经后状态：OR=0.35；95％CI：0.13-0.92）。
结论：我们的研究结果表明，较高的DQI-I评分与较低的BrCa发生率相关。根据我们的研究,健康的饮食模式对于预防BrCa至关重要。
