Abstract：
Six previously undescribed prenylated C6-C3 derivatives (1-6) were isolated from the root of Illicium ternstroemioides A. C. Smith. Their structures were elucidated based on extensive spectroscopic analyses (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of 1-3 were determined using electronic circular dichroism (ECD), and Mo2(OAc)4 induced circular dichroism (ICD). Compound 3 exhibited weak activity against Coxsackievirus B3 with an IC50 value of 33.3 µM, and compound 5 exhibited more potent activity against Coxsackievirus B3 with an IC50 value of 6.4 µM.
摘要：
从八角菌A.C.Smith的根中分离出六种先前未描述的异戊二烯化C6-C3衍生物（1-6）。基于广泛的光谱分析(UV，IR,1D和2DNMR，和HRESIMS）。使用电子圆二色性（ECD）确定1-3的绝对构型，Mo2(OAc)4诱导圆二色性(ICD)。化合物3对柯萨奇病毒B3表现出弱活性，IC50值为33.3μM，化合物5对柯萨奇病毒B3表现出更强的活性，IC50值为6.4μM。
